The Summary Of Professor Feng Xinsong’s Experiences About Osteoporosis And The Clinical Research About Invigorate Kidney, Support Splen And Activating Blood

ObjectiveFollowing the academic thinking of professor Feng Xinsong treatmenting osteoporosis, to evaluate the effect of the Methods about invigorate kidney, support Splen and activating blood on the E2、OPG and IGF-Ⅰ cytokine axis and clinical therapeutic effect in the post-menopause osteoporosis through the clinical research.MethodBy the random and prospective clinical research,53post-menopause osteoporosis patients were randomly divided into treatment group and control group. Treatment group were given Gu kang and calcium tablets, control group were given Xianlinggubao capsule and calcium tablets. Both groups take medicines for6months. After six months treatment, we will observe the count-scores of clinical symptom, BMD, E2, OPG and IGF-Ⅰ in the serum,and statistical analysis of the resultsResultsThere were53post-menopause osteoporosis patients completed the follow-up and treatment. The results indicate:First, the excellence rate in treatment group (29%) was higher than in control group (24%), and the total efficient rate in treatment group (86%) was higher than in control group (80%), there were no significant statistical differences in the two groups(P>0.05). Second, BMD and E2of post-menopause osteoporosis patients were lower than healthy women. Under the same circumstances, E2in the serum and BMD in the from2to4lumbar vertebrae were higher than before treatment. E2had a significant statistical difference (P<0.01), but BMD had no significant statistical difference (P>0.05) in the two groups. Third, OPG and IGF-Ⅰ of post-menopause osteoporosis patients were higher than healthy women. After six months treatment, OPG in the serum were significant lower, but IGF-Ⅰ in the serum was higher than before. There were no significant statistical difference (P>0.05) in both groups.ConclusionHormonoprivia is a important reason for post-menopause osteoporosis. The change of level OPG, IGF-Ⅰ in the serum have important role in post-menopause osteoporosis. To sum up, Gu kang improve clinical therapeutic effect, increase the level of BMD、E2、and IGF-Ⅰ, and decrease the level of OPG. So, it can be seen that the therapy of the chinese herbal drugs Gu kang regarding the Methods about invigorate kidney, support Splen and activating blood is a total mode of regulation on the body through the clinical research.