| The Northwest Dryness Syndrome is not an independent entity, but a group of TCM syndrome characterized by dry oronasal, skin and throat, tussiculation and other uncomfortable symptoms. The Northwest Dryness Syndrome includes one main syndrome and five accompanying syndromes. The main symptom is Lung, skin and opening of the body dryness syndrome, accompanying syndromes are deficiencies of essence and blood of the liver and the kidney syndrome, the lung and heart wind-fire pathogen syndrome, yin deficienties of the heart and kidney syndrome, yin deficiencies of the lien and stomach syndrome and endogenous dampness syndrome. Opening of the body disease is pathological change in eye, mouth, nasal, throat, etc. Skin disease is pathological change in facial skin, whole skin, etc. This paper discusses correlation between the Northwest Dryness Syndrome and skin and opening of the body disease.Objective:Discuss attack rate correlation between the Northwest Dryness Syndrome and skin and opening of the body disease in Khotan, Turpan, Kami, Urumchi, Xinjiang. Analyse correlativity in etiology and pathogenesis and clinical manifestation between them. Provide theoretical basis for the prevention and cure of same treatment for different diseases of the two kinds of disease. Contents and Methods:Analyse epidemiology data based upon2844patients of the Northwest Dryness Syndrome that we have investigated in Khotan Region in2004. Applied clinical epidemiology Case-control study method, survey patients with opening of the body disease such as chronic rhinitis, chronic pharyngitis, chronic conjunctivitis etc. and skin disease such as chronic urticaria, cutaneous pruritus etc. by questionnaires about prevalence of the Northwest Dryness Syndrome and main syndrome and accompanying syndrome of the Northwest Dryness Syndrome in3hospitals in Kami Region,4hospitals in Turpan Region and3hospitals in Urumchi Region, and healthy urban and rural residents (no significant difference in age, sex, ethnic etc.) as control, then assess the date collected. Furthermore explore influence of disease condition and TCM syndrome, influence degree of dryness syndrome of skin and opening of the body disease to the Northwest Dryness Syndrome. The survey data was inputted through EPIDATA3.0, after that, another20%of the questionnaires were picked for random check, and checked the consistency of the data by relevant statistical software. Then, the final analysis research database was completely formed. In the process of statistical analysis, we used SPSS16.0statistical software for general statistical analysis such as t-test, ANOVA, while using of cluster analysis other multivariate statistical methods. In this paper, we used statistics indicator such as disease condition integral, disease condition index, main syndrome and accompanying syndrome of the Northwest Dryness Syndrome integral, dryness syndrome index, TCM syndrome contribution coefficient, TCM syndrome index. And applied TCM theory to give reasonable explanations about correlativity between the Northwest Dryness Syndrome and skin and opening of the body disease.Results:The Northwest Dryness Syndrome attack rates were56.07%and56.25%respectively in patients suffered opening of the body disease and skin disease in Khotan Region, both is higher than the control group with attack rates12.97%and12.50%(P<0.01). The relative risk (OR) of chronic rhinitis, chronic pharyngitis, oral ulcer, chronic urticaria, cutaneous pruritus caused by the Northwest Dryness Syndrome were3.18,2.63,4.23,3.51and3.48respectively. Compared main syndrome and accompanying syndrome of the Northwest Dryness Syndrome integral, dryness syndrome index of patients with skin and opening of the body disease with control group, the results showed that one main syndrome and five accompanying syndromes were encountered in clinical syndrome. Thereinto, dryness syndrome index of opening of the body disease with main syndrome and five accompanying syndromes of the Northwest Dryness Syndrome were0.31,0.28,0.22,0.33,0.23and0.15, all were greater than or equal to0.15, and less than0.35, they were moderate dryness syndrome; dryness syndrome index of skin disease with endogenous dampness syndrome was0.14, less than0.15, it’s slight dryness syndrome, the other dryness syndrome index of skin disease were0.30,0.29,0.26,0.33and0.22, all were over0.15, and less than0.35, they were moderate dryness syndromes.The Northwest Dryness Syndrome attack rates were62.97%and48.82%respectively in patients suffered opening of the body disease and skin disease in Turpan Region, Kami Region, Urumchi Region, both were higher than the control group with attack rates14.69%,14.96%(P<0.01). Compared main syndrome and accompanying syndrome of the Northwest Dryness Syndrome integral, dryness syndrome index with each other, the results showed that opening of the body disease with the main syndrome and the lung and heart wind-fire pathogen syndrome were frequent in clinical syndrome. Thereinto, main syndrome of the Northwest Dryness Syndrome index was0.31, over0.15, it’s moderate dryness syndrome; the lung and heart wind-fire pathogen syndrome index was0.15, less than0.15, it’s slight dryness syndrome. In patients of opening of the body disease, there were significant differences (P<0.01) on disease condition integral and disease condition index among patients with the Northwest Dryness Syndrome and control group. The main syndrome of the Northwest Dryness Syndrome, the lung and heart wind-fire pathogen syndrome, yin deficienties of the heart and kidney syndrome, yin deficiencies of the lien and stomach syndrome and endogenous dampness syndrome were frequent in clinical syndrome of skin disease, deficiencies of essence and blood of the liver and the kidney syndrome was infrequent. The main syndrome and four accompanying syndromes dryness syndrome index were0.23,0.18,0.29,0.20and0.16respectively, all were over0.15, they were moderate dryness syndromes. dryness syndrome index of skin disease was higher than that of opening of the body disease, the results show that the Northwest Dryness Syndrome of the former was more serious than latter. In patients of skin disease, there were no significant differences (P>0.05) on disease condition integral and disease condition index among patients with the Northwest Dryness Syndrome and control group.The concrete conditions of all syndromes involved by the two kinds of disease in the three regions as follows. The Northwest Dryness Syndrome attack rate was47.50%among patients of chronic rhinitis, it’s higher than control group with attack rate15%(P <0.01), the main syndrome and the lung and heart wind-fire pathogen syndrome were frequent in clinical syndrome among the Northwest Dryness Syndrome. There were significant differences (P<0.01) on disease condition integral and disease condition index among patients of chronic rhinitis with the Northwest Dryness Syndrome and control group. The lung and heart wind-fire pathogen syndrome correlated with chronic rhinitis most in cluster analysis. The Northwest Dryness Syndrome attack rate was72.02%among patients of chronic pharyngitis, it’s higher than control group with attack rate15.69%(P<0.01), the main syndrome was frequent in clinical syndrome among the Northwest Dryness Syndrome. There were significant differences (P<0.01) on disease condition integral and disease condition index among patients of chronic pharyngitis with the Northwest Dryness Syndrome and control group. The main syndrome correlated with chronic pharyngitis most in cluster analysis.The Northwest Dryness Syndrome attack rate was63.01%among patients of chronic conjunctivitis, it’s higher than control group with attack rate18.70%(P<0.01), the main syndrome were frequent in clinical syndrome among the Northwest Dryness Syndrome. There were no significant differences (P>0.05) on disease condition integral and disease condition index among patients of chronic conjunctivitis with the Northwest Dryness Syndrome and control group. Deficiencies of essence and blood of the liver and the kidney syndrome correlated with chronic conjunctivitis most in cluster analysis, secondly it’s main syndrome, and the next was lung and heart wind-fire pathogen syndrome.The Northwest Dryness Syndrome attack rate was49.20%among patients of chronic urticaria, it’s higher than control group with attack rate16.34%(P<0.01), the main syndrome and five accompanying syndromes were encountered in clinical syndrome among the Northwest Dryness Syndrome. There were no significant differences (P>0.05) on disease condition integral and disease condition index among patients of chronic urticaria with the Northwest Dryness Syndrome and control group. The lung and heart wind-fire pathogen syndrome correlated with chronic urticaria most in cluster analysis.The Northwest Dryness Syndrome attack rate was48.68%among patients of cutaneous pruritus, it’s higher than control group with attack rate23.03%(P<0.01), the main syndrome and the lung and heart wind-fire pathogen syndrome, yin deficienties of the heart and kidney syndrome and yin deficiencies of the lien and stomach syndrome were frequent in clinical syndrome among the Northwest Dryness Syndrome. There were no significant differences (P>0.05) on disease condition integral and disease condition index among patients of cutaneous pruritus with the Northwest Dryness Syndrome and control group. Yin deficiencies of the lien and stomach syndrome, endogenous dampness syndrome and the lung and heart wind-fire pathogen syndrome correlated with cutaneous pruritus strong in cluster analysis. Conclusion:1. Opening of the body disease and skin disease attack rates are higher in people with the Northwest Dryness Syndrome than control group, the Northwest Dryness Syndrome is important risk factor for skin and opening of the body disease.2. Main syndrome and accompanying syndromes of the Northwest Dryness Syndrome are different from each other in patients of opening of the body disease and skin disease. Thereinto, main syndrome and the lung and heart wind-fire pathogen syndrome are frequent in opening of the body disease, the other accompanying syndromes are not prominent; besides the above two syndromes, yin deficienties of the heart and kidney syndrome, yin deficiencies of the lien and stomach syndrome and endogenous dampness syndrome are also common in skin disease, only deficiencies of essence and blood of the liver and the kidney syndrome is infrequent.3. Disease condition with the Northwest Dryness Syndrome is more serious than non dryness syndrome among patients of opening of the body disease, this relationship is mainly embodied in chronic rhinitis and chronic pharyngitis; but there are no significant differences between disease condition with the Northwest Dryness Syndrome and non dryness syndrome among patients of skin disease either chronic urticaria or cutaneous pruritus.4. The Northwest Dryness Syndrome is not only influences disease condition of skin and opening of the body disease, but also impacts TCM syndrome of two kinds of disease in different degree. |
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