| Objective:This study aims to explore the Chinese medicine academic thought origin of Wen Zhen-ying, summarize her characteristics of pediatric academic theory and clinical experience, and improve our own clinical experience at last.Methods:1 Follow the teacher in clinical diagnosis; observe seriously of the teacher’ four diagnostic methods and take notes carefully.2 Study the teacher’s works:"Medical case of Wen Zhen-ying".Seriously study and deeply understand the teacher academic thought.3 Read the four classics of Chinese Medicine, the pediatrics of TCM ancient books, Combine the essence of classic TCM and teacher’s clinical experience. Excavate deeply teacher’ academic thought origin.4 Retrieve literature related about modern Pediatrics of TCM, and study these TCM pediatrics professors’academic characteristics to make preparations for the excavation work followed.5 Take clinical survey on 150 cases of children with asthma, then make the further classification of constitution, Analyze the data by statistical method to get the results;6 Classify and analyze teacher Wen’s prescriptions for 145 treatment cases of children with acute asthma, using analysis method of descriptive statistics, such as the frequency and constituent ratio, in order to extract prescription principles and medication essence; 7 Apply the teacher’s experience of asthma treatment in clinic, and 60 cases of asthma will been treated. Observe the curative effects by scientific research method. And then test the treatment effects.The main content of this thesis is divided into three parts.Part 11 Explore the Chinese medicine academic thought origin of Wen Zhen-ying by reading the classics of Chinese Medicine and ancient books of TCM pediatrics.2 Study the academic characteristics of modern TCM pediatrics doctors by modern literature retrieval, in order to dig deeper into teacher’s own academic thoughts characteristic and clinical experience.Part 2Summarize and research Wen Zhen-ying’s pediatric academic theory from the following six aspects.1:Holistic Medicine;Strengthen healthy qi to eliminate pathogens;Attention to spleen and stomach;Attention to nourishing yin;Attention to nutrition and health care;Development view. Summarize and research the pediatric clinical experience of Wen Zhen-ying. Mainly from the Nourishing and Qi, strengthening body resistance and eliminating evil to treat recurrent respiratory tract infection. Strengthening the spleen and replenishing qi, strengthening healthy to therapy of infantile diarrhea, dispelling wind and moistening lung to treat pediatric asthma, surporting heaithy energy to treat Cancer,strengthening spleen and softening liver in treatment of children with ADHD, TIC disorder, allergic children face inspection characteristics, advocate" special and multiple effect "medicine application experience and other seven aspects were discussed.Part 3The paper summarized the commonly used drugs of Wen Zhen-ying teacher in treatment of children asthma, and discussed in detail combined with the theory of traditional Chinese medicine and modern pharmacological research.1 The constitution of asthma children is a kind of personal idiosyncrasy classified by the TCM theory. But at present, there has been no further discussion on which type of TCM constitution this idiosyncrasy tends to be. According to experience of Wen Zhen-ying teacher in treatment of allergic disease for many years, referencing to Chinese Medicine Institute issued in 2009 April the" TCM constitution classification and judgment"(ZYYXH/ T157-2009), and combining of pediatric physiologic and pathologic characteristics, we have taken epidemiological investigation and research on 150 asthmatic children and their parents by constitution questionnaire, and analyzed the further classification of children with asthma in TCM constitution types.2 Research has summarized, refined Wen Zhen-ying teacher’s common prescriptions and drugs in the treatment of children asthma, and discussed in detail using the theory of traditional Chinese medicine combined with modern pharmacological research.3 According to Wen Zhen-ying teacher’s clinical treatment experience of pediatric asthma, using the rule of nourishing yin to dispelling wind, moistening lung and relieving asthma, adopting Wen’s empirical prescription of expelling wind and relieving asthma, we treated children patients of mild to moderate acute exacerbation of asthma, took clinical observation and used bronchodilator agents and leukotriene modifiers which confirmed by current modern medicine for the control. We found that there were no significant difference between treatment group and the control group in the clinical curative effect. The research indicated that the prescription of empirical prescription of expelling wind and relieving asthma took good effect on treating asthma acute attack of children.Results:On the basis of inheritance and according to our clinical practice, discusses the theory of "treatment hypersensitiveness disease from muscular interstices".Publish 3 articles as the first author identity, of which 2 published in core journals.Conclusion:Wen Zhen-ying’s academic theory and experience are precious wealth of TCM pediatrics. It is very necessary to inherit, excavate and spread of Wen Zhen-ying’s academic thought and clinical experience in pediatrics of traditional Chinese medicine, especially good for the development of high level technical talents. Through three years of study with teacher Wen, We have taken effectively mining and summarization on teacher’s academic thought and clinical experience. Our professional theory level and clinical skills have made great progress consequently This study includes two parts:literature review and clinical research.Purposes:1. Adopt clinical investigation on 150 cases of children with asthma included their constitution characteristic, to understand physical type distribution and the personal idiosyncrasy for further classification, in order to take syndrome differentiation and treatment according to the physical characteristics, and guide the children and their parents to living or nursing.2. Study on treatment rules of pediatric asthma acute episode invented by Wen Zhen-ying teacher, in order to learn her medication principles and experience essence for pediatric asthma acute episode treatment.3. Treat children attacked by asthma acute episode using Wen Zhen-ying teacher’s empirical prescription of expelling wind and relieving asthma, observe curative effect compared with the control group, so as to provide a new idea for the Chinese medical treatment of children with acute asthma.Methods:1. Using literature search tool, study the literature about pediatric asthma treatment with traditional Chinese medicine and Western medicine, master ancient and modern, Chinese and Western Medicine viewpoint on children asthma pathogenesis and treatment methods; 2. Take clinical survey on 150 cases of children with asthma, then make the further classification of constitution, Analyze the data by statistical method to get the results; 3.Classify and analyze teacher Wen’s prescriptions for 145 treatment cases of children with acute asthma, using analysis method of descriptive statistics, such as the frequency and constituent ratio, in order to extract prescription principles and medication essence; 4. The treatment group took Wen Zhen-ying teacher’s empirical prescription of expelling wind and relieving asthma. The control group used the combined medication treatment for Beta-2 adrenergic receptor agonists (salbutamol sulfate sustained release capsules), leukotriene modifiers (Montelukast Sodium Chewable Tablets), which is recognized by western medicine for comparison. Take statistics analysis and observe curative effect.Result:1. All of 150 asthmatic children have personal idiosyncrasy classified by the TCM theory, but if divided further,123 cases belong to the type of Yin deficiency or tend to be Yin deficiency, accounting for 82%; deficiency and Qi tendency in 4 cases,4 cases belong to the type of Qi deficiency or tend to be Qi deficiency, accounting for 2.66%; 13 cases belong to deficiency of both Qi and Yin, accounting for 8.66%; 5 cases belong to the type of Yin deficiency and tend to be Qi deficiency, accounting for 3.33%; 2 cases belong to the type of Qi deficiency and tend to be Yin deficiency, accounting for 1.33%; 3 cases belong to the type of Dampness and Heat, accounting for 2% of.2. Statistical analyze teacher Wen’s prescriptions for 145 cases of children with acute asthma, using every kind of drug application frequency of total drugs percentage. Nourishing Yin drugs account for the largest proportion, accounting for 34.81%; followed by the medicine for relieving cough and asthma, the dispelling wind medicine, account for 21.85%,17.64%; and followed by the heat-clearing drug and drugs for regulating Qi flow, respectively accounting for 8.53%,8.48%; and the drugs for invigorating blood circulation take the smallest proportion,0.90%.Take each drug application frequency accounted the total number of prescriptions percentage to statistics, Fang Feng is applied mostly in the dispelling wind medicine, occupy 100%, Chai Hu with vinegar and Qin Jiao take second place, respectively,37.24%, 36.55%; Wu Mei, Wu Weizi and Ke Zi are the most in Yin-nourishing drugs, account for more than 96% times, followed by Huang Jing and Bai He,93.79%, 62.07% respectively; Shi Changpu take the most proportion in the medicine for the treatment of cough and asthma, occupy 98.62%, followed by Bai Guo, Zi Yuan, respectively occupy 93.10%; Sue Geng is the mostly used drugs for regulating Qi flow, accounted for 76.55%;Zi Cao is the mostly used drugs for invigorating blood circulation, accounted for 8.28%.3. The research indicated that the prescription of expelling wind and relieving asthma takes good effect on treating children asthma acute attack. Compared to the control group used the combined medication treatment for salbutamol sulfate sustained release capsules and Montelukast Sodium Chewable Tablets, which is recognized by modern medicine, the Wen’s prescription has better clinical efficacy, ether in the overall efficacy or in the controlling of cough main disease and nose, skin, stool minor disorders. The two group treatment effects have no significant difference in statistics.Conclusions:Children with asthma have personal idiosyncrasy classified by the TCM theory, and most of them belong to the type of Yin deficiency if divided further. Combining with the children’s constitution, use the rule of nourishing yin to dispelling wind, moistening lung and relieving asthma to treat children with acute asthma may be clinical effective, it also be help to improving the stuffy nose, itchy skin, dry stool and other related symptoms at some extent,... |
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