As the economic development pattern changes, S&T (science and technology) is playing an ever-stronger role in supporting and guiding economic and social development. S&T resources are much relied on both at national and regional level to enhance capacity building in innovations. Up to now, quite a number of research works have been made in regional economy, while less were seen in regional S&T. Even less attention is given to the characteristics of spatial distribution of S&T resources that affect regional capacity in innovations. This essay is aimed to probe the characteristics and causes for spatial distribution of S&T resources in China, therefore providing some basic research input that will facilitate S&T development at regional level, improve the efficiency of S&T resource allocations, and enhance regional capacity in independent innovations.Methodologies in regional economics are applied in the essay, where total S&T resources, spatial distribution of structures and comparisons between S&T and the economics are studied to outline the spatial distribution characteristics of S&T resources in China. On the basis of theoretical and practical approaches, multi-regression analysis is applied to explore the causes for spatial distribution of S&T resources in China. Furthermore, an optimized spatial distribution model for S&T resources are established, and the strategy for spatial development of S&T is proposed. Based on the analysis, the following observation are made:Firstly, by distribution characteristics of S&T resources, the country could be categorized into five, namely the Central S&T Pole, Seaboard S&T Belt, Inland S&T Circle, S&T Developing Zone and S&T Less Developed Region, each of which presents differentiated characteristics in S&T development.
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