Clinical Research On The Treatment Of Insomnia With Electroacupuncture And Gan Mai Da Cao Tang (Kanbakutaisoto)

Objective To investigate the impact of depression degree, anxiety degree, sleepiness degree, sleep quality index of insomnia patients treated by electro-acupuncture with taking Gan Mai Da Cao Tang.Methods 60 patients conformed to the diagnostic criteria consistent insomnia and inclusion criteria, were randomly divided into two groups, the treatment group treated by electroacupuncture with taking Gan Mai Da Cao Tang, and the control group treated by taking Gan Mai Da Cao Tang,30 cases each. In the aspects of the treatment group, we stimulates the main point including Zhaohai, Shenmai, Shenmen, Yintang, Sishencong, Anmian. and stimulates the matching point including Xinshu, Pishu, Zusanli. When getting qi, we used a electric acupuncture apparatus with the sparse-density wave for 20 minutes after the density wave for 10 minutes.All patients were treated one time per day,5 days per week,4 week for a course of treatment, and 2 months for a observed period of treatment. Then, All patients including the treatment group and the control group took Gan Mai Da Cao Tang, three times per day (morning, afternoon and evening), Each 0.05g/kg, with warm water,1 months for a course of treatment, and 2 months for a observed period of treatment. We evaluated the improvement of insomnia of every patient and the clinical efficacy according to the following items, (1) Self-rating depression scale (SDS), (2) Self-rating anxiety scale (SAS), (3 The Pittsburgh Sleep Quality Index (PSQI), and we used "the guiding principle of clinical research on new drugs" by Ministry of Health of the People's Republic of China in 1993 as a clinical indicator criteria to determined the clinical efficacy of insomnia.Results (1) In the score evaluation of Self-rating depression scale (SDS), there is a statistically significant difference between after treatment and before treatment of the treatment group (P<0.01), and there is a statistically significant difference between after treatment and before treatment of the control group (P<0.01). The difference between after treatment of the treatment group and control group, is also statistically significant difference (P<0.01). (2) In the score evaluation of Self-rating anxiety scale (SAS), there is a statistically significant difference between after treatment and before treatment of the treatment group (P<0.01), and there is a statistically significant difference between after treatment and before treatment of the control group (P<0.01). there is a statistically significant difference between after treatment and before treatment of the treatment group (P<0.01), and there is a statistically significant difference between after treatment and before treatment of the control group (P<0.01). (4) In the evaluation of percentage rate of sleep, there is a statistically significant difference between after treatment and before treatment of the treatment group (P<0.01), and there is a statistically significant difference between after treatment and before treatment of the control group (P<0.01). (5) In the score evaluation of the Pittsburgh Sleep Quality Index (PSQI), there is a statistically significant difference between after treatment and before treatment of the treatment group (P<0.01), and there is a statistically significant difference between after treatment and before treatment of the control group (P<0.01), and the individual results, including sleep quality, sleep latency, sleep time, sleep efficiency, sleep disturbances and daytime function, were the same. (6) In the evaluation of clinical efficacy, there is a statistically significant difference between the treatment group and the control group (P<0.05). However, healing rate of the control group was 60.00%, and healing rate of the treatment group was 76.67%.Conclusions (1) The treatment of electroacupuncture and Gan Mai Da Cao Tang can improve the depression degree of Insomnia patients, and it is more effective than the treatment of Gan Mai Da Cao Tang only. (2) The treatment of electroacupuncture and Gan Mai Da Cao Tang can improve the anxiety degree of Insomnia patients, and it is more effective than the treatment of Gan Mai Da Cao Tang only. (3) The treatment of electroacupuncture and Gan Mai Da Cao Tang can improve the Sleepiness degree of Insomnia patients, and it is more effective than the treatment of Gan Mai Da Cao Tang only. (4) The treatment of electroacupuncture and Gan Mai Da Cao Tang can improve the percentage rate of sleep of Insomnia patients, and it is more effective than the treatment of Gan Mai Da Cao Tang only. The treatment of electroacupuncture and Gan Mai Da Cao Tang can improve the sleep quality of Insomnia patients, including sleep quality, sleep latency, sleep time, sleep efficiency, sleep disturbances and daytime function, and it is more effective than the treatment of Gan Mai Da Cao Tang only. (6) The clinical efficacy of the treatment of electroacupuncture and Gan Mai Da Cao Tang is superior to the treatment of Gan Mai Da Cao Tang only.Above, this study demonstrated that the treatment of electroacupuncture and Gan Mai Da Cao Tang does have a therapeutic role, not only can improve the depression degree, the anxiety degree, the sleepiness degree and the percentage rate of sleep in patients, but also can promote recovery of sleep quality, sleep latency, sleep time, sleep efficiency, sleep disturbances and daytime function, and it's clinical efficacy is significantly superior to the treatment of Gan Mai Da Cao Tang only. Therefore, this study shows that the treatment of electroacupuncture and Gan Mai Da Cao Tang is suitable for insomnia patients with type of deficiency of both heart and spleen, and is worthy of clinical application.