| Hyperplasia of prostate is a common disease in older men. With the population aging process, the incidence rate will further increase, seriously affecting quality of life of older men, or even complications, threatening the patients'life. It has been one of the most important diseases that infects the health of old men and become a very topic in the 21st century.Warm needling moxibustion is a therapy combined with needling and moxibustion, which has the Chinese characteristics in the treatment of many diseases, especially diseases with deficency syndrome by TCM differentiation of symptoms and signs. This therapy can play an unique effect. In this study, We intend to apply warm needling moxibustion therapy in patients with chronic hyperplasia of prostate of deficency syndrome, and hope that this study will explore an effective way to treat this disease and provid a new safe and effective treatment program for it has a higher disease incidence in present population.ObjectiveThis study use clinical epidemiology and clinical scientific research, mathematical statistics and analytical method, by randomized controlled study, the objective of this reseach is to observe the clinical effect of warm needling moxibustion conbined with Chinese herbs in treating chronic hyperplasia of prostate of deficency syndrome (deficency of kidney or deficency of liver and kidney) and to confirm the therapy of Warm needling moxibustion has an exact effect n the exact effect in treating this disease.MethodsAccording to the diagnostic criteria of retention of urine/uroschesis in guiding principles of new drugs in Chinese medicine clinical research, we collected 50 cases of patients with chronic hyperplasia of prostate who met the criteria from Taiwan Chenzhengang'TCM Clinical during February 2008 and February 2009. Applying randomized single-blind method, we diveded the reseach objects into test group and control group in the ratio of 1:1. The patients in test group were treated with warm needling moxibustion conbined with Chinese herbs, and the other ones treated with pure Chinese herbs. One week for a course of treatment.After two course, observing the changes on prostate volume, residual urine volume and its clinical effect before and after treatment.Using EpiData 3.1 software to establish database and statistical software SPSS15.0 to complete statistical analysis.Measurement data with means±tandard deviation (x±S), numeration data with composition ratio (%), measurement data between groups with T-test (heterogeneity of variance with t'test or rank sum test), before and after itself with paired-samples T-test or Wilcoxon paired rank sum test, Categorical data between groups with Chi-Square test, ranked data between groups with Wilcoxon rank sum test. Making use of statistical graphics software Graph Pad Prism 4.03 to complete statistical graph.Results5o qualified clinical cases were collected and the patients were all over 50 years old. Warm needling moxibustion conbined with Chinese herbs group(simplely called test group) 25 cases, the youngest 50 years old, the oldest 73 years old, mean age 61.34±5.32, the shortest disease duration 3 years, the longest 15 years, mean disease duration 8.34±2.78 years; Chinese herbs goup(control group) 25 cases, the youngest 51 years old, the oldest 66 years old, mean age 58.92±4.96, the shortest disease duration 1 years, the longest 12 years, mean 6.89±2.63 years.Comparability of baseline characteristics of patients in the test group and control group in age, duration, severity, prostate volume and residual urine volume before treatment, the difference had no statistical significance,meaning the baseline characteristics of the two groups were comparable.The effect of main study indicators:the difference was not statistically significant (P> 0.05) in improving prostate volume in the two group. Comparing the difference of each group on this aspect before and after treatment, the results showed no statistically significant difference in both groups, indicating that these two therapies had no impact on Prostate volume. The difference was statistically significant (P<0.05) in improving residual urine volume in the two group. Comparing the difference of each group on this aspect before and after treatment, the results showed statistically significant difference in both groups, indicating that both therapies had effect on improving urinary tract obstruction and the test group was larger in changing the amount of residual urine volume than the control group. It means that the effect of warm needling moxibustion combined with Chinese medicine group was more effective than the control group in relieving urinary tract obstruction.About clinical efficacy:25 patients in the test group,5 remarkably effective cases,17 effective cases, total effective rate was 88.0%; 25 patients in pure Chinese herbs group,0 remarkably effective cases,16 effective cases, total effective rate was 64.0%. Comparing therapeutic effect and the total effective rate of the two groups,the differences were statistically significant and the total effective rate of the test group was higer than that of control group. After received the treatment of warm moxibustion combined with Chinese medicine, the patients'clinical symptoms were evidently improved, showing that this therapy has an remarkable effect.ConlcusionThe therapy of warm needling moxibustion conbined with Chinese herbs can relieve the synptoms of urinary tract obstruction and has a remarkable effect. This study has initially proved that this therapy can significantly raise the clinical effet on treating chronic hyperplasia of prostate of deficency syndrome and is worthy of promotion. |
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