Clinical Observation On Hyperplasia Of Prostate (Moist Heat And Blood Stasis) With Acupuncture Added Chinese Herbs

ObjectiveThis randomized controlled clinical research adopts the clinical epidemiological methods, clinical research methods and statistical methods. It takes pure Chinese herbs therapy as comparison and observes the clinical curative effect of applying acupuncture and Chinese herbs to cure hyperplasia of prostate (moist heat and blood stasis). It discusses the difference of the clinical effect and provides the basis for the clinical treatment of hyperplasia of prostate.MethodsThe research has 70 patients of hyperplasia of prostate (moist heat and blood stasis), who were treated in Chinese Medicine clinic in Taiwan from February 2008 to February 2009 and who met the case selection standards.All the patients were divided into two groups (the warm needle acupuncture added Chinese herbs group, and pure Chinese herbs group), with 35 in each group at the rate of 1:1. The pure Chinese herbs group were treated with the QIANLIE KANG TABLETS, taking 2.5g a time, tid, P.O. The warm needle acupuncture added Chinese herbs group were treated with warm needle acupuncture and taking the QIANLIE KANG TABLETS the same way as the pure Chinese herbs group. A week was a course. All the patients were treated for four weeks. After every week, patients'clinical symptom, IPSS, PSA, quality of life, and urodynamic study, etc. were measured. Before and after the treatment, check the safety indexes.Use software EPIDATA 3.1 to set up the database and use software SPSS 15.0 for statistics and analysis. The measurement material is expressed by x±S and the numeration material by constituent percentage. For the interclass comparison of the measurement material, take F test (for heterogeneity, take Kruskal-Wallis H rank sum test); for the interclass multiple comparison, take q test (Newman-Keuls); for self circa comparison, take the t pair test or pair rank sum test. For the interclass comparison of the classified material, take x2 test. For the interclass comparison of the ranked material, use Kruskal-Wallis H rank sum test. Draw the statistics graphs with software Graph Pad Prism 4.03.ResultsThis research collects 70 cases with no difference in two groups in age, course of disease, clinical symptom, IPSS, PSA, quality of life, and urodynamic study, etc.The warm needle acupuncture added Chinese herbs group has significant curative effect for hyperplasia of prostate (moist heat and blood stasis) treatment. The control rate is 22.2%; the efficient rate is 25.0%; the effective rate is 41.6%,;the total effective rate is 88.9%.According to the standard of international advisory council, the warm needle acupuncture added Chinese herbs group has more significant curative effect for hyperplasia of prostate (moist heat and blood stasis) treatment. The control rate is 37.4%; the efficient rate is 48.7%; the total effective rate is 86.1%.After the treatment, the patients'clinical symptom, IPSS, PSA, quality of life, and urodynamic study changes a lot. The therapy of warm needle acupuncture added Chinese herbs can effectively improve the patients' clinical symptom, urine condition, and quality of life, and lower the patients'residual urine volume and urine time. In a word, the therapy of warm needle acupuncture added Chinese herbs, has better effect than the therapy of pure Chinese herbs, and it is safe without side effect.ConclusionBased on the clinical results, the warm needle acupuncture added Chinese herbs therapy can cure the hyperplasia of prostate (moist heat and blood stasis) noticeably. It can adjust the patients'clinical symptom, urine condition, and quality of life, lower the patients'residual urine volume, and shorten the urine time. It is safe and has no side effect. It is an effective method for hyperplasia of prostate (moist heat and blood stasis) and deserves being popularized.