Study On Pathogenesis Syndromes And Treatment Method Of Sanjiao Qi Movement Be Obstructed By Statistical Analysis On Medical Records

Objective:Collect ancient and modern Sanjiao medical records and mentor's Sanjiao medical records. Through analyzing these records' syndromes and mathematical statistical analysis of the drug, to derive regularity of distribution about the syndromes and drug,and then from it can decuce Sanjiao to relate in pathogenesis law. Provide a reference for TCM Clinical Diagnosis and Treatment from the Sanjiao Qi movement be obstructed as the basic pathogenesis of complex diseases.Methods:To separately establish the mentor's Sanjiao syndrome database on the Treatment of Medical Records, the mentor's Sanjiao drug database on the Treatment of Medical Records, the Ancient and Modern Sanjiao syndromes database on the Treatment of medical records, the Ancient and Modern Sanjiao drug database on the Treatment of Medical Records.160 records of the mentor Sanjiao on the Treatment of Medical records and 341 records of the Ancient and Modern Sanjiao on the Treatment of Medical records syndromes and drugs are to be processed in frequency analysis, cluster analysis, factor analysis by using the computer statistical software. Apply Chinese medicine theory, especially the Sanjiao the theories to analyze the statistical results.Results:1.Mentor's Sanjiao on the Treatment of medical records syndromes performance cluster analysis results can be divided into 5 representatives of the different pathogenesis of the combination of type.:①Sanjiao Qi depression,Qi and clear fluid not diffusion②upper hyperactivity of liver yang, channel barrier③deficiency of both Qi and blood, Sanjiao Qi depression④Sanjiao, heat being obstructed interior⑤, Qi stagnated in Sanjiao, liver fire invading stomach.The factor analysis extracted common factor of 14. Sanjiao theories similar pathogenesis basis consolidated into six categories:①primordial Qi deficiency in Sanjiao,②fire stagnated in Sanjiao, Qi depressionin liver and gallbladder③Qi stagnated in Sanjiao hyperactivity of fire in liver channel④Qi stagnated in Sanjiao, the upper and lower barrier⑤Qi stagnated in Sanjiao, incoordination between ying and wei⑥Qi stagnated in Sanjiao, superficies and interior barrier. Corresponding to the main card of the core pathogenesis as follows:fatigue, back pain, chest tightness, chest pain, pink tongue. Tongue, thin white fur, thin pulse, headache, tinnitus, dry eyes, eye swelling, palpitation palpitations, dry mouth, thirst, abdominal distension, abdominal pain, disturbed sleep soundly at night, dark red tongue, bloating, belching, acid regurgitation, heartburn, red tongue, slippery pulse, dizziness, mouth pain, pulse wiry.2. Mentor's Sanjiao on the Treatment of Medical Records Drug clustering analysis of the results can be divided into 7 types which represent in different pathogenesis of types:①Qi stagnated in Sanjiao, stagnant pathogen of Shaoyang②Qi stagnated in Sanjiao, incoordination between ying and wei③Qi stagnated in Sanjiao, pathogenic Qi accumulated in lung and stmach.,④upper hyperactivity of liver yang, channel barrier⑤hyperactivity of liver fire, liver fire invading hear⑥primordial Qi deficiency, dampness-heat diffused downward,⑦liver Qi invading stomach, Qi stagnation and blood stasis.Factor analysis to extract the common factor of 19, according to the principles of pathogenesis similar Sanjiao related theory combined into 11 categories:①Qi stagnated in Sanjiao, liver fire invading stomach②Qi stagnated in Sanjiao, incoordination between ying and wei③Qi stagnation in Sanjiao, channel stoppage④Qi stagnation and blood stasis in stomach⑤Qi stagnated in Sanjiao, hyperactivity liver yang causing wind⑥intense heat in Sanjiao, liver fire invading heart⑦pathogenic Qi accumulated in lung and stomach⑧Qi stagnated in Sanjiao⑨tagnant pathogen of Shaoyang⑩Qi stagnated in Sanjiao. Qi accumulated in large intestineO Qi deficiency in Sanjiao, dampness-heat in lower jiao.Corresponding to the core pathogenesis of drugs are:Bupleurum, Cinnamon Twig, white peony root, peony root, Citrus aurantium, Citrus aurantium, skullcap, Jujube, Codonopsis, ginger, ginger Pinellia, Magnolia, Trichosanthes root, turmeric, Polygonum cuspidatum, Poria the Atractylodes Toosendan, Yuan Hu, the Soviet Union stems, yams, raw malt, Scorpio, the powder of antelope's horn3.Ancient Modern Sanjiao on the Treatment of medical records syndromes performance cluster analysis can be divided into 7 types of combination of different pathogenesis.:①Qi stagnated in Sanjiao②heat stagnated in Sanjiao③dampness hampering Sanjiao Qi movement,incoordination between superficies and interior④water diffusion in Sanjiao⑤dampness hampering Sanjiao Qi movement, incoordination between zang-fu viscera⑥heat stagnation in heart nutriment⑦eversed flow of Qi in Sanjiao.The factor analysis extracted 22 common factors. According to The Sanjiao theories similar pathogenesis principle, they can be merged into 10 categories:①ampness hampering Sanjiao Qi movement②Qi stagnated in Sanjiao③water diffusion in Sanjiao④intense heat in Sanjiao⑤invasion of heart nutriment by heat⑥channel barrier⑦diffusive dampness-heat in Sanjiao⑧reversed flow of Qi in Sanjiao⑨ncoordination between ying and wei⑩primordial Qi deficiency.Corresponding to the main syndrome performance of the core pathogenesis:stretching, deafness, hearing loss, chest tightness, abdominal swelling of the liver nausea, the appetite to be lessen and digest to be bad. nausea, vomiting, the stools not to be completely, abdominal pain, diarrhea, fever, dry mouth, thirst, and desire to more drinking, greasy fur, white fur, yellow tongue coating, slippery pulse, pulse thin, thready pulse, the pulse string Jueleng limbs, cough, expectoration, edema, shortness of breath, breathlessness, not lying4.Ancient and Modern Sanjiao on the Treatment of medical records drug cluster analysis results can be divided into 6 types of the different pathogenesis combinations. On behalf of 7 types:①dampness hampering Sanjiao Qi movement②water diffusion in Sanjiao③hyperactivity of fire in Sanjiao④invasion of heart nutriment by heat⑤cold-dampness disturbing Sanjiao⑥deficiency of both Qi and clear liquid⑦Qi stagnated in Sanjiao, pathogenic Qi accumulated in lung and stmach.The factor analysis to extract the common factor of 21, Sanjiao theories similar pathogenesis basis consolidated into 9 categories:①heat depression in Sanjiao②water diffusion in Sanjiao③dampness hampering Sanjiao Qi movement④diffusive dampness-heat in Sanjiao⑤invasion of heart nutriment by heat⑥cold-dampness disturbing Sanjiao⑦pathogenic Qi accumulated in lung and stmach⑧Qi deficiency in Sanjiao⑨Qi stagnated in Sanjiao.Correspond ing to the core pathogenesis of drugs are:almonds, cardamom, magnolia bark. Pinellia. talc. Alisma. Polyporus, Poria red, through the grass. orange peel, Dafu Pi, rugosa. skullcap, turmeric, citrus aurantium. berberinecalamus, reed, Trichosanthes, honeysuckle, rhino horn, Citrus aurantium, forsythia, fresh raw land, black bean sauce. Conclusion:1.A mentor Sanjiao on the Treatment of Medical Records analysis results reflect certain characteristics within the Qi movement be obstructed sick Sanjiao syndromes, pathogenesis, therapy. Ancient and Modern Sanjiao on the Treatment of medical records reflect certain characteristics of exogenous disease Sanjiao Qi movement be obstructed syndrome, pathogenesis and therapy.2.The pathogenesis characteristics of internal injuries Sanjiao Qi movement be obstructed are:for Sanjiao Qi as the core, often see incoordination between ying and we, incoordination between zang and fu viscera, upper and lower barrier.superficies and interior barrier, channel barrier. And because of Qi and clear fluid not diffusion, dampness hampering Sanjiao Qi movement, heat depression in Sanjiao potential pathogenesis.The most closest conjunction of viscera are liver and are prone to have changes in the pathogenesis of the liver by fire, liver yang. The most associated obvious internal organs are the stomach, colon, and bladder. The weakness of Yuan Qi could be the foundation within injury Sanjiao Qi movement be obstructed and the associated internal organs with the Sanjiao deficiency are kidneys. The Qi depression frequently appears in Shaoyang Gallbladder Channel of Foot suggesting the close relationship of gall bladder and Sanjiao in the pathogenesis sense, Sanjiao Qi movement be obstructed could be Sanjiao internal organs, Sanjiao, gall internal organs, gall bladder through the Shaoyang system as a whole Qi movement not be fluently.3. The syndrome's characteristics of injuries Sanjiao Qi movement be obstructed are: Qi stagnation syndrome are more commonly, fiery syndrome more common, along with the liver channel disease more common, performance is hyperactivity of heart-liver fire upper hyperactivity of liver yang. stagnation of liver Qi.4. The therapy's characteristics of injuries Sanjiao Qi movement be obstructed are: "dredging and coordinating method" as the basic treatment of ideas, mainly using of the law "harmony" from "8 methods of treatment", cooperated with the use of a clear method, fill method, dismount. For different pathogenesis, often use Qi liver Qi and Liver purging fire, soothe the liver meridians, Qi and blood circulation, declared down the lung and stomach, catharsis and purging heat, tonic Pei-yuan, and the specific treatment method. The used Core of drug combinations are similar to Chaihuguizhi decoction and Sini powder.5.The pathogenesis characteristics of exogenous disease of the Qi movement be obstructed Sanjiao are:the main air-caused by the Sanjiao Qi movement be obstructed moisture resistance, common pathogenesis is stagnation of Qi, dampness, heat Yu, the water stopped. the association of Visceral pathogenesis in focus the spleen is not health movement Stomach does not fall mainly, often involving with coke lung declared down and the next focus bladder gasification unfavorable. Disease potential evolution of the law is evil from the Sanjiao easily into the heart of the camp. There is lack of vitality, Sanjiao and alpine block Sanjiao the pathogenesis of type.6. The syndrome characteristics of the exogenous disease Sanjiao are:based on the principle of syndrome-based Sanjiao stagnation of dampness, common spleen health movement, not fall Stomach, lung Vision loss and bladder gasification adverse syndromes. Prone to have Sanjiao damp heat syndrome7.The therapy's characteristics of exogenous disease Sanjiao Qi movement be obstructed are:based on the principle of treatment of activating Qi and removing dampness, resolving of dampness with aromatics, promoting diuresis with drugs of tasteless flavor, invigorating spleen for eliminating dampness and sorts of eliminating dampness methods Mainly use the methods of dispersing lung Qi, regulating stomach descending adverse Qi invigorating spleen and replenishing Qi, promoting diuresis with drugs of tasteless flavor and other methods to help removing dampness and activating Qi.The heat-clearing formula are more often used.When intense heat in Sanjiao, need to pre-heart nutriment The taken core drug combinations are similar to ganlu xiaodu micropills and sanren decoction. 8.Qi stagnation in Sanjiao is the common pathogenesis base of exogenous disease and the injury the Sanjiao Qi movement be obstructed. The corresponding syndromes and pathogenesis of Qi and clear fluid not iffusion exist in both exogenous disease and internal injuries9.Exogenous disease and internal injuries have differences between the characteristics of pathogenesis and the characteristics of syndromes:Qi movement be obstructed correlation of the exogenous disease Sanjiao organs injury in the pathogenesis of the syndrome characteristics are related to water metabolism. The closes of the organs within the injury Sanjiao Qi movement be obstructed correlation wang yang decline are related. The reason may be that exogenous disease mainly affects the Sanjiao function, abnormal,Qi and clear fluid not diffusion main; within the injury affected the Sanjiao organs yang regulatory function, resulting in strength, Sanjiao, organs yang not diffusion.Innovation:1. Collecting a large number of medical records about Sanjiao treatment from Ancient to Modern. Using mathematical statistics analysis system to summarize Sanjiao related to Qi movement be obstructed medical records syndrome characteristics, governance characteristics of the method. To sum up, the combination of drugs can be used as a basic reference. To clarify the characteristics of the exogenous disease Sanjiao Qi movement be obstructed pathogenesis. and to explore the similarities and differences between and within the pathogenesis of injury Sanjiao Qi movement be obstructed and possible causes. Providing the basis for the dialectical use of the traditional Sanjiao range from exogenous febrile disease extends to the internal injuries and Miscellaneous Disease.2. For the first time we use the mathematical statistics analyzing method to conclude mentor's Sanjiao on the Treatment of clinical medical records of complex diseases. Such kind of diseases are the basic pathogenesis of Sanjiao Qi movement be obstructed. Diseases locations cover a wide range. The performance of syndrome is complex. Pathogenesis is composite by diverse factors. The treatment of single viscera is very well. more common in clinical medicine, but generally not attach importance to it. The overall theory of governance from the Sanjiao can have a good effect. Through the analysis of medical records, to establish the syndrome characteristics. governance characteristics of the method and pathogenesis characteristics and to sum up as a basic reference for drug combinations. For clinical diagnosis and treatment provided a reference, help to improve the TCM internal medicine clinical diagnosis and treatment levels for such diseases.Insufficient:The range of selected Ancient and Modern Sanjiao on the treatment of medical records have a little disadvantges so the results only reflect some of the features among exogenous disease Sanjiao Qi movement be obstructed in the syndrome, pathogenesis, on the therapy. Although reflecting the objective situations of Sanjiao theory in clinical use, then more one-sided. Subject to gather more information in the future and a wider range of statistics of medical cases to get a more comprehensive conclusion.