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Traditional Chinese Medicine Constitution Theory Research On Patients With Rheumatoid Arthritis

Posted on:2012-11-19Degree:DoctorType:Dissertation
Country:ChinaCandidate:Z L LingFull Text:PDF
GTID:1114330368975685Subject:Traditional Chinese Medicine
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BackgroundRheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic destructive joints. The disease is mainly with hands, wrist, knee, ankle and foot joints polyarthritis symmetry. Accompanied by fever, anemia, subcutaneous nodules and lymph nodes and other extra-articular manifestations can occur, as well as a variety of auto-antibodies in serum. Without the proper treatment of rheumatoid arthritis can be delayed healing, and even lead to joint deformity. Rheumatoid arthritis was 22-60/100,000, the prevalence was 0.34%. The tribes of Pima Indians in North America, the prevalence rate as high as 5%. In Finland, the disease prevalence rate is 2%. The different of prevalence may be related to genetic factors.RA is of traditional medicine "Bi disease" category. "Bi disease" is the result of human suffering wind, cold, wet, heat the invasion of the evil, blood is yin pathogenic factors caused the disease off. To bones, muscles, joint pain, numbness, weight forward, flexion and extension negative and joint swelling, burning and other clinical manifestations. According to the different causes can be divided into "XingBi", "HanBi", "ShiBi", and "ReBi". The recurrent attacks and progressive gradually is the clinical features. The main pathogenesis is that the Blockage of qi and blood cannot nourish tendons and joints.The Chinese constitution theory think that the process of constitution is a living human body, in the innate endowments and acquired formed the basis of morphological, physiological and psychological status comprehensively, and the relative stability of the inherent characteristics of human growth and development process of the formation with natural and social environment suited to human personality traits. Chinese Physical Science has formed a relatively complete theoretical system of Chinese medicine can be widely used and effective clinical practice of guidance and health rehabilitation.According to previous research and related literature accessed, we conclude the incidence of rheumatoid arthritis with the Chinese constitution has some correlation, but for Hong Kong-Shenzhen area of rheumatoid arthritis medicine physical analysis and description of the characteristics of a large number reported in the literature yet. This study of 588 cases of Shenzhen and Hong Kong Chinese patients with rheumatoid arthritis type of distribution and physical characteristics, as Hong Kong and Shenzhen RA patients with the diagnosis, treatment and prevention to provide guidance, and individualized treatment to provide some evidence.Objective1. Analysis of 588 cases of physical distribution of Chinese RA patients;2.Analysis of 588 cases of RA patients with TCM syndrome types of constitutions and distribution;3.Summarizes 588 cases of RA patients with physical medicine and TCM syndrome type of TCM arthralgia distribution and classification of the dialectical and Herbal Prescription guidance.Method:The 595 RA patients perform a sample survey from March 2009 to October 2010 between Hong Kong and Shenzhen hospital. We choose the Chinese Society of Traditional Chinese Medicine "issued by Chinese constitution classification and determination" in the standardization of TCM constitution to determine, and Traditional physical factors using self-assessment score sheet for relevant factors. Uniform training investigators to help fill the scene in the questionnaire,588 valid questionnaires were received. Survey of 400 cases in Hong Kong (68.02%), Shenzhen City,188 cases (31.97%), in which the United Christian Service of the Hong Kong Chinese University of Traditional Chinese Medicine Clinical Research Centre 270, United Christian Nether sole Community Health Service Jockey Club and Le Community Health Centre 203,115 Hospital of Shenzhen City. The age is from 16 to 70 years.All questionnaire data input by the Commissioner of trained software used EpiData3.1 double to double entry, after approval by the inspectors to export the data, statistical analysis with SPSS 17.0. Measurement data to mean+standard deviation, Comparison between groups using independent sample t test and correlation analysis using spearman,, all statistical tests are used both sides, P<0.05 is considered the test significant difference.Results:1.The general situation of 588 cases of Hong Kong and Shenzhen region with rheumatoid arthritisThe general information of 588 cases of patients:Age:(51.58±16.72), median 51, range 16 to 70 years; Sex:Male 220 patients (37.41%), female 358 cases (62.59%); Nationality:Chinese 583 (99.15%) cases of other peoples 5 (0.85%) cases. Birthplace:Guangdong Province,339 (58.55%) cases, Hong Kong 114 (19.69%) patients, and other provinces in 126 (21.76%) cases. Residential area in Hong Kong 138 (32.03%) cases,399 (67.97%) cases. Education:high school and below 443 (75.34%) cases, college or university 130 (22.11%) cases, undergraduate or 15 (2.55) cases. Marital Status:Single 99 (16.84%) cases, married 464 (78.91%) cases, divorce 4 (0.68%) cases; cohabitation status:cohabiting 123 (79.35%) cases, separation of 32 (20.65%) patients; disease Season:Spring incidence of 338 (57.48%) patients, the incidence in summer 33 (5.61%) patients, fall incidence of 11 (1.87%) cases,523 incidence in winter (88.95%) cases; family history:a family history of 196 (33.33%) patients; have chronic diseases 446 (75.85%) cases.2.588 cases of Shenzhen and Hong Kong Chinese patients with rheumatoid arthritis region physical distributionIn this study,588 cases in Hong Kong and Shenzhen in patients with rheumatoid arthritis showed a single physical body type and mixed type (2 or 3 physical body type of the phase and appear). Gentleness 54 (9.18%) cases, biased mass 534 (90.82%) cases, of which only a single physical type of 76 cases (12.9%),2 body types,33 cases (5.61%) and 3 body types 399 cases of physical types (67.86%). Specifically, 588 cases of rheumatoid arthritis, according to the proportion of front to back the size of the nine body type is:yin and yang deficiency and blood stasis quality of 124 cases (21.1%), yin deficiency and blood stasis and heat quality of 102 cases (17.3%), Yang and quality of phlegm and blood stasis in 62 cases (10.5%), gentleness 54 (9.2%) patients, Yang and blood stasis and special intrinsic quality of 34 (5.8%) patients, Qi yang deficiency and blood stasis and quality of 34 (5.4%) cases, heat and qi deficiency and quality of 26 (4.4%), Yang and Yin and humid 23 (3.9%) patients, Yang and quality of heat and blood stasis 18 (3.1%) cases.The physical types distribution of 142 RA patients without chronic disease is that:Yin and blood stasis and heat transfer in 31 cases (21.8%), gentleness in 23 cases (16.2%), Yang and Yin and blood stasis quality 18 (12.7%), and qi deficiency and heat transfer in 13 cases (9.2%), Yang and Yin and heat transfer in 8 cases (5.6%), Yang and quality of phlegm and blood stasis in 7 cases (4.9%), yang deficiency and blood stasis and special intrinsic quality of 6 patients (4.2%), Qi and Yang deficiency and the intrinsic quality characteristics in 2 cases (1.4%), qi and qi mass in 2 cases (1.4%), yin deficiency and heat transfer 2 cases (1.4%), heat and blood stasis and special intrinsic quality of 2 cases (1.4%), quality of qi and blood stasis in 1 case (0.7%), yang and yin deficiency in 1 case (0.7%), Yang and Yin and phlegm in 1 case (0.7%).588 cases of 9 RA patients is to determine basic physical types of patients:The gentleness of 54 cases (9.2%), Qi deficiency 50 cases (8.5%), Yang and quality of 331 cases (56.3%),340 cases of yin deficiency (57.8%), phlegm 98 cases (16.7%), heat transfer of 210 cases (35.7%). blood stasis quality 405 (68.9%), qi quality of 44 cases (7.5%), special intrinsic quality of 46 cases (7.8%).3. Syndromes distribution and physical analysis of the correlation 588 cases of RA patients,230 cases of heat Blockage card (39.1%), alpine Blockage card 156 cases (26.5%),149 cases of kidney cold syndrome (25.3%), liver and kidney in 39 cases (6.6%) Blockage of blood stasis card 14 (2.4%).In 588 cases of RA patients, Yang and the quality and distribution of 5 syndromes correlated (χ2=6.07, P<0.0001), yin deficiency syndrome and the distribution of 5 correlated (χ2=15.49, P=0.0038), phlegm and the distribution of 5 syndromes correlated (χ2=6.07, P<0.0001), heat transfer and distribution of 5 syndromes correlated (χ2=11.99, P=0.0174), blood stasis Quality and distribution of 5 syndromes correlated (χ2=41.39, P<0.0001),5 special intrinsic quality and the distribution of syndromes associated (χ2=23.76, P<0.0001). Peaceful nature, quality and qi deficiency syndrome and quality of 5 is not relevant. 4.9 kinds of physical and comparison of related factors9 body types of people and "living environment", "sleep", "interpersonal relationship" "work environment" "contact water" "Smoking" "Drinking" "pressure sense", "hi a cold drink," "negative emotions" " Exercise circumstances "relevant factors such as sub-item 17 in the" living environment"," sleep state "" relationships "" work environment "" smoking, "" drinking """ pressure sense "a note on the purpose of 9 statistical difference significance. The remaining six were not significant.Compared with the gentleness and 9 factors were statistically significant (P <0.05). Specifically, in the "living environment" entries, the quality of Qi deficiency and qi significant (P=0.001); Yang nature, yin deficiency phlegm, blood stasis quality heat transfer were statistically significant (P=0.000); special compare the intrinsic quality of the quality and peace was not statistically significant, in the "sleep"entry in the quality of statistical significance deficiency (P=0.022) qi mass (P=0.001) other physical P=0.000, the differences were Statistically significant. In the "drinking"entry in the Qi deficiency (P=0.493), phlegm (P=0.224) and the special intrinsic quality (P=0.113) with no significant difference in alcohol consumption, are "smoking"entry, the deficiency Quality (P=0.147) and phlegm (P=0.065) with no significant difference between peace and quality in the "exercise circumstances " under the entry Qi deficiency (P=0.0.053), yin deficiency (P=0.0.279), heat transfer (P=0.0.443), and qi quality (P=0.446) were compared with the gentleness no significant differences.Conclusions1.588 cases of RA onset in winter and spring season for many, most associated with other chronic diseases.2/3 of patients have a genetic history2.588 cases of RA patients to quality as the basic physical characteristics of blood stasis, and folders on this basis, composed of other basic body types in patients with physical types.3.588 cases of RA patients with physical medicine and TCM syndrome type was significantly correlated types.4. RA patients compared with the peaceful transfer from the environment, smoking, alcohol consumption, stress, mood, sleep, interpersonal relationships Dengjun significantly lower than gentleness.5. For RA patients should be identified while in the dialectical constitution, its dialectic and Herbal Prescription classification and provide guidance.
Keywords/Search Tags:Rheumatoid Arthritis, Features of Chinese Medicine Constitution
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