| Study BackgroundHeat sensition moxibustion therapy is in the last few years the Chinese medicine clinical diagnosing and treating engineering research hot spot project.It's an innovative therapy mainly carries on using combustion moxa stick in the patient body surface inquired about point of organism has the unique transmission phenomenon hotly to the moxibustion and carries on long-enduring suspended moxibustion, and maintains to heat-Sensitive phenomenon vanishing, to achieve the purpose of treating patients with diseases.Duration of chronic bronchial asthma is a common disease in clinical respiratory, the epidemiology investigation showed the whole world approximately has 160,000,000 asthma patients. According to《Bronchial Asthma Guide)) definition bronchial asthma is Chronic inflammatory airway disease, that is participation by many kinds of cells (Such as Eosinophils,mastocyte and T lymphocytes,Neutrophil,Airway epithelial cells) and the cellular elements.This kind of chronic inflammation causes the gas channel high reactivity, Usually reversible with widespread variable airflow limitation and causes the respite which, the short of breath, the chest manifests suddenly repeatedly stuffy or symptoms and so on cough, often and (or) early morning manifests suddenly, the aggravating at night, the most patients may alleviate voluntarily or after the treatment alleviation.Regarding this sickness card, the doctor practicing western medicine take the hormone,β2-Receptor Agonist, bronchodilator agents as the main treatment medicine, is good to the symptom control effect. The Chinese medicine unifies therapy union pharmacological treatment this sickness and so on moxa, cupping, foaming moxibustion by the acupuncture, may also have certain treatment result.Western drug is currently using hormone drugs control more than the disadvantage of most of them have some side effects, and long-term use of large economic burden, not able to adapt in all groups of patients;Chinese medicine treatment must have a physician in the diagnosis and treatment in hospitals and long-term acupuncture treatment, patients tend to fear there will affect the patients continued to receive treatment compliance.We attempt from the Traditional Chinese Medicine therapy moxibustion to seek for one method, one kind may enable the patient to accept from the psychology, and convenient, simple, does not have the side effect, One kind may enable the patient to accept from the psychology, and convenient, simple, does not have the side effect, taking advantage of by oneself or family member's assistance, can the long-term self-health care application treatment method.Objective:Uses the acupoint heat sensitization Moxa therapy treatment bronchial tube asthma chronic duration and as control of Western medicine Seretide, anticipated obtains with the western medicine Seretide repeat close or the same curative effect, and for clinical care asthma to treat the technology to provide a new plan.Observation acupoint heat sensitization Moxa therapy treatment bronchial tube asthma's patient, time between treatment moxibustion transmission and moxibustion quantity relationsResearch content:The first part:The system reorganized the traditional Chinese medicine to the heavy breathing card, to breathe heavily the card understanding, the development, the treatment medicine and the method。Understands the modern medicine to the bronchial asthma's definition, the cause of disease and the function machine-made, the clinical symptoms. And commonly used method, treatment, conventional medicine, to explore, evaluate their advantages and disadvantages of both. The second part:Regarding affects the moxa curative effect factor and the moxibustion feeling and the moxibustion quantity modern research carries on the elaboration Carries on the elaboration to the heat sensitive moxibustion in the clinical practice present situation. The discussion said in the channels and collaterals the heat sensitive moxibustion transmission effect the significance, and carries on the observation to the heat sensitive moxibustion quantity in the modern heat sensitive moxibustion treatment's literature. Carries on the discussion to the hot sensitive moxibustion's method good and bad points, like ingredient of moxa flue and function, course of treatment manpower application question.The study is under the support of subject, acupoints heat-sensitive moxibustion treatment of asthma(persistent) from the National Science and Technology Support Program. By observing the improvement of Pulmonary function test (FEV1, and PEF) and symptoms of asthma patients who are treated by the acupoints heat-sensitive moxibustion therapy and Seretide (50μg/25μg), we could evaluate the clinical effect of acupoints heat-sensitive moxibustion therapy incuring the asthm a (persistent).Observes between transmission phenomenon which and moxibustion quantity reciprocity this topic course of treatment produces.The moxibustion feeling's appearance and vanishing are the moxibustion quantity saturated bases, this therapy stressed that certainly must enable the heat sensitive acupuncture point moxibustion quantity to achieve sufficiently saturated, can make the best clinical progress.Methods:The same for the national multi-center randomized controlled clinical trial, were randomly assigned by central randomization method, controlled by the China Academy of Traditional consent, were randomized to the results of stochastic systems by using the central web publishing. The 72 patients met the inclusion criteria, the multi-center randomized into the group, thermal moxibustion group (treatment group) 36 cases of Seretide group (control group) 36 cases.Because the heat sensitive moxibustion group has 1 example to take the number operation question not to integrate stochastically, in the course of treatment, some 3 examples fall off; Seretid group has 2 examples to fall off, integrates the statistical case heat sensitive moxibustion group 32 examples finally, Seretid group 34 examples.The treatment group implements the hot sensitive moxibustion law 3 months, each time treats the time lower limit 30 minutes, the upper limit 90 minutes, already was by now sensitive in the compartment the disappearing quantity to be possible to complete the treatment fully.The treatment investigation spot in the back of the Bladder Meridian of Foot-taiyang after two outer conductors, FeShu (BL13) separates between the GeShu (BL17) two level lines the regions Former chest first rib clearance, second rib clearance from inside to outside to 6 inches range. The hand-held elliott, in investigates in the heat sensitization acupoint selects 1 heat sensitization phenomenon most obvious acupuncture point to carry on hangs the moxibustion, every other 2 minutes brush off the ash (time not to surpass 10 seconds) and adjust moxa roll and the skin distance, maintains the enough heat degree, take has the heat penetration, to expand the heat, the heat transfer and acupoint heat sensitization phenomena and so on non-hot feeling as the standard. To the heat sensitive point which investigates has hung the moxibustion one by one.Treatment group is treated by acupoints heat-censitive moxibustion therapy for 3 months,30 to 90 minutes once, until the heat-sensitive aecupoints lose their specialty and turn in to common acupoints. At the first month, start treatment continuelyFor once a day for 8 days at the very beginning, and then 12 times treatment at the left 22 days, make sure there are is times treatment each month during the later 2 month (Treatment is no more than once a day). Control group is treated by Seretide 50μg/250μg (salmeterol xinafoate 50μg/flutieasone propionate 250μg), which is produced by Glaxosmithkline Corporation, one Inhalationa once, twice a day. Observe Period lasts for 3 months "Before treatment and after 3 months, treatment, every patient should cheek the Pulmonary function. During the period of there seareh,the score of symptoms after treated for half a month, for 1 month, for 2 months and for 3 months should be taken down for comparison. Observed indicators to evaluate the curative effete are PEF (Peak Expiratory Force) and FEV (Expiratory Volume in First sceond) in the pulmonary funetion tests, scores of symptom and effeetive rate. The patient first diagnosis starts to treat continuously for 8 days, daily 1 time, in the first month latter 22 days guarantee 12 treatments; Latter two month guarantee every month 15 times (every day≤1 time). Control group, the British company GlaxoSmithKline's Seretide 50μg/250μg (salmeterol 50μg/fluticasone propionate 250μg), each 1 suction,2 times a day for 3 months.Therapeutic efficacy:To observe the cycle of time before treatment and 3 months,6 months after treatment, lung function (FEV1, PEF), and treatment, 3 months,6 months after treatment, clinical medicine and asthma symptoms scores Situation.Observation moxibustion feeling and moxibustion quantity relations target: 1. whether there is hot sensitive spot; 2. and traditional acupuncture point position degree of polymerization; about 3. both sides position to be whether symmetrical; about 4. both sides moxibustion feeling intensity feeling; 5. gives off heat violently the sensitive phenomenon time (by one minute, in five minutes, and is bigger than five minutes for grouping); 6. executes heat sensitive spot which Moxa treats, divides into the front, the back; 7. in the moxibustion feeling the most intense direction (divides into:Four limbs, proliferation, heat penetration); 8. the pair of hot sensitive moxibustion's method receptivities (accept, general, repel); 9.6 kind of heat sensitive phenomenon performance situation; 10 total moxibustion time (moxibustion quantity).Regarding the smoke oversized solution, the author self-restraint one transportable, the info clerk is simple, of air exhaust device outside the expense small advantage, may fast, large scale discharge the smoke, reduces the patient and operator's illness.Results1. Judging from the gender composition, the female contracts asthma's proportion to be higher than the male slightly。The age concentrates mostly between 30-50 years old, the course is long, may be 50 years.2. Mainly for junior middle school and high school or technical college degree educational level, In the transaction cognitive degree have a certain level, The proportion of alcohol and tobacco exposure from the point of view, better self-control, and compliance for the medication or treatment would be helpful. 3. Thermal moxibustion group and western medicine group after 3 months, all can have remarkable curative effect, outcome quite. In the long term, thermal moxibustion therapy through systemic airframe adjustment function, symptoms continue to get better, from asthma symptoms in control the number of partial control into control increases.4. The men and women under the similar treatment way and the different treatment way, do not have the obvious difference. May say that the sex to treats the way not to have the obvious difference.5. Weight, blood pressure factor for the acceptable heated the sensitive moxibustion and Western medicine Seretide treatment and efficacy, no significant effect. However, western medicine group that have an effect on heart rate Seretide, to a certain extent.6. Chinese medicine practitioners from symptom scores and individual symptoms score look at the total score, systemic symptom, respiratory condition, cold and sweat out, thirsty, etc, sickness integral results:Two groups treat 3 months later, and treats the latter 6 month-long revisit time, the integral has the improvement, the symptom can have the change for the better. Two groups of comparisons do not have the difference, two groups of effects quite.7. Before two groups treat, with treat 3 months, to treat in the latter 6 month group to compare, around the treatment compares asthma symptom integral to have the remarkable improvement, the process treats for 3 months, the western medicine treats asthma symptom integral improvement to surpass the heat sensitive moxibustion group. Treats the latter 6 month two groups of comparisons, the function quite.8.The two groups before treatment and therapy for 3 months,6 months after treatment in comparison, before and after the treatment of asthma symptoms integral have compared improved markedly, three months after treatment, western medicine treatment of asthma symptom scores improve superior thermal moxibustion group. Six months after treatment, the two groups of comparisons, the effect is fairly. Two groups in lung function index PEF and FEV1 testing results, two groups of evaluation quite. PEF treatment of 6 months after testing results than thermal moxibustion group 9. The medicine group has an example side effect, mainly produces swallows ill, the sound hoarse symptom, how processes after just right for the illness and educates to apply drugs, improves. The heat sensitive moxibustion group has not seen the obvious side effect.10. Completes the sensitive disappearing quantity full treatment, asthma patient symptom has the distinct improvement. And the heat sensitive phenomenon stimulation rate is high.11. Around the average treatment time as 59.61±12.12 the minute, unifies this topic hot sensitive moxibustion patient to treat the curative effect result union determination, the moxibustion quantity achieves the sensitive disappearing quantity to complete the treatment to have the curative effect fully12. The majority patients may give off heat violently in 5 minutes the sensitive phenomenon, the back present the proportion to compare the front area to be high.13. In the most obvious moxibustion feeling form's comparison the former four limbs direction are most.14. The heat sensitization acupoint and the traditional acupuncture point reference uniformity is high 72.8%; The degree of polymerization height does not affect and about the acupuncture point position symmetrical situation and the obvious moxibustion feeling direction form15. Observes to half of example inferior bodies about the both sides to the moxibustion feeling symmetry is consistent.16. About in the both sides feeling degree difference is more obvious by left side.17. The acupoint heat sensitization 6 big phenomenon rules by many kinds of appear together, for the heat penetration, expands the heat, the radiation common, the few parts have the non-hot feeling.18. The moxibustion quantity does not have the difference in the around spot, does not receive the hot sensitive phenomenon stimulation time speed and the most obvious moxibustion feeling direction influence. May see that the heat penetration, expands the heat, the heat transfer and the non-hot feeling, not obvious difference.Conclusion The heat sensitive moxibustion is accurate to the bronchial asthma's treatment curative effect, is close with the western medicine Seretide effect, on clinical may recommend the application between the moxibustion feeling and the moxibustion quantity has certain relation, must specifically further enlarged sample and sickness plants the research, is clear about the relevance.The sensitive disappearing quantity is the curative effect judgment standard fully.
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