The Relationship Of Insular Cortex And The Pathogenesis Of Sleep Apnea-Hypopnea Syndrome And Its Conduction Pathway

The Sleep Apnea-Hypopnea Syndrome (SAHS), a common sleep-related breathing disorder, is characterized by repetitive upper-airway obstructions and disruptive snoring during sleep. It often results in apnea and oxygen desaturations. When a complete or partial airway obstruction is manifested by a complete cessation or substantial reduction (i.e., > 50%) in oronasal airflow of at least 10 sec, the respiratory event is defined as apnea or hypopnea, respectively. The common complications of the syndrome are always involved in the cardio-cerebrovascular system. Therefore, the syndrome severely affects the quality of the patient's life and threatens to the life of the patients.The pathogenesis of this syndrome is not yet clear todate. To clarify the pathogenesis and the mechanism of it has important significance for the prevent and treatment of the syndrome.Considerable progress has been made over the last several decades in our understanding of the pathophysiology of both central and obstructive sleep apnea. Central sleep apnea, in its various forms, is generally the product of an...