Objectives: To identify the risk factors associated with congenital microtia, and put forward its preventive measures.Methods: A case-control, retrospective study was performed. A total of 207 cases of congenital microtia and 209 age-frequently-matched controls were interviewed individually according to the uniform questionnaire. The variables analyzed included: gender, education of father and mater, pregnant age of father and mater, first trimester intrauterine infection and medication, fervescence, retinoic acid, hypemia, hypertension, threatened abortion and tocolysis, vomiting of pregnancy and antemetic, psychic trauma, Uterine disease, abnormal pregnancy, pesticide, diazepam, clomifene, excessive drinking and smoking of parents, parity, abortion (spontaneous and induced) , X-ray, residence fitment, attending defect, tea and family history. The available data were analyzed by chi-square test and multivariate Logistic regression model.Results: Compared to the controls, there were not statistically differences in the cases in age and race. The factors, such as gender, pregnant age of father and mater, first trimester intrauterine infection and medication, fervescence, hypemia, threatened abortion and tocolysis, psychic trauma, abnormal pregnancy, pesticide, excessive drinking and...
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