Studies On The Mechanisms Of Attenuation,synergy And Antineoplasm Of Hippocampus Marrow-engendering Pill To Women's Malignant Tumor

In this research, taking BALB/c mouse immunosuppressive models made by DDP.. CTX i.p. and 60Co- y irradiation as objects of study, with advanced techniques such as 3H-TDR endosmosis.. MTT method.. FCM marrow cell agarose gel electrophoresis and immunohistochemistry.. optic microscope electronmicroscope, influences of Hippocampus Marrow- Engendering Pill to T.B cell function .. IL-2 level and marrow cell multiplication degree of model-mouse are studied. The results show that Hippocampus Marrow-Engendering Pill can obviously increase T lymphocyte transformation function of mouse inhibited by radiotherapy.. chemotherapy ,regulate the abnormity of T cell subpopulation CD4~ICD8~,increase the IL-2 level in peripheral blood, help to resume the hematopoietic function of inhibited marrow hemoietic stem, improve the multiplication degree of marrow cell. In the bases, taking Si 80-mouse implanted tumor SKOV3 oophoroma model-mouse as objects of research, through immunohistochemistry researches such as degree of inhibition tumor to implanted tumor.. optic microscope.. electrorimicroscope and cell apoptosis regulator P53.. BCL-2, Hippocampus Marrow-Engendering Pill is proved to have some antitumor function ,which can inhibit the tumor growth of S 180-mouse implanted tumor, obviously increase the function of killer tumor of SKOV3 ophoroma model-mouse DDP~, improve the apoptosis of tumor cell. The article elaborates the immunoregulation function of Hippocampus Marrow-Engendering Pill at the cellular and molecular level, studies the happening , development, prognoses, deeply explains internal relations of the mechanism of inhibiting tumor attenuation synergy and immunologic injury of compound agent of TCM with tumor, provides theoretical and experimental foundation for clinical application of Hippocampus Marrow - Engendering Pill.