The Quality Of Sleep Apnea In Patients With Scoliosis

Background:Scoliosis has many effects on breathing, which often accompanied by the decrease of lung function. As the aggravation of scoliosis, respiratory failure is common in the patients. The sleep breathing quality in the night is closely related to lung function. However, the incidence of sleep-related breathing problems in this population is less well known. There was little research on sleep breathing quality in scoliotic patients without other diseases.Objective:1. The study aims to explore the differences between the quality of sleep in scoliotic patients and the normal population.2. To study the sleep breathing quality of the patients with scoliosis in different body positions during the sleep.3. To study the difference of blood oxygen saturation between patients with scoliosis and normal people.4. To study the relationship between lung function and thoracic Cobb angle in patients with scoliosis.5. To explore the differences of sleep breathing quality between different types of scoliotic patients and healthy people.Methods:A total of forty-six scoliotic patients and ten healthy populations were included in the prospective study. They had been monitored by Wrist sleep monitor to obtain the state of their sleep. The index of sleep breathing, blood oxygen saturation and sleep fragmentation were obtained to find the diversity between the two groups. Meanwhile, the medical records, X-ray of positive lateral position of the entire spine and the results of lung function were also obtained. According to statistical analysis, the sleep breathing quality between the two groups was compared. And the relationship between the scoliosis Cobb angle, the lung function and sleep quality was also explored.Results:1. Thirty-five females (76.0%) and eleven males (24.0%), a total of 46 subjects were included in the study with the ages ranging between 11 and 32 (mean 16.2 ± 4.8). The mean BMI was 20.0 ± 3.6 kg/m2, while another group comprised by the healthy control had 10 subjects with eight females (80%) and two males (20%). The ages between 12 and 20 (mean 17.7±2.8) and the mean BMI was 18.7±1.9kg/m2.2. There were no statistic difference about the RDI between the two groups (p=0.208) and no significant relationship was revealed between the Cobb angle of thoracic scoliosis and the RDI(& AHI) scores in patient group (p=0.651, p=0.345, p>0.05).3. And there were no statistic difference about the SaO2 between the two groups. There were no relationship between the thoracic Cobb angle and the minimum SaO2 in patients with scoliosis.4. But 63.3% of patients got low RDI scores in the consistent position of thoracic scoliotic direction during sleep while it was nearly equal in the two directions in control group. Besides, there were no statistic difference about the RDI between the patient group and the control group.5. It was also found that the FEV1 (Act/Pred) showed statistical correlation with the thoracic Cobb angle (p=0.001).6. Compared with the control group respectively, the idiopathic scoliosis group and the congenital scoliosis group shown no statistical correlation.Conclusions:Scoliosis shows no significant influence in sleep breathing quality. Compared with the control group, there was no significant difference in sleep breathing quality in patients with different types of scoliosis. Sleep in the same positon with thoracic scoliotic direction may benefit for patients with scoliosis.