| Objective:Through clinical observation and analysis of the changes of various headache indexes,TCM syndrome scores and safety indexes in patients with occipital great neuralgia of Taiyang meridian headache syndrome who take occipital neuralgia prescription before and after,this study aims to achieve the objective evaluation of the clinical efficacy and safety of occipital neuralgia prescription in the treatment of Taiyang meridian headache syndrome of occipital great neuralgia,so as to further enrich the TCM treatment methods of occipital great neuralgia and provide scientific clinical trial basis for clinical treatment promotion.Methods:64 cases were collected according to inclusion and exclusion criteria.The treatment group was treated with occipital neuralgia prescription,and the control group was treated with gabapentin orally,which was randomly divided into the experimental group and the control group 32 cases each.According to the established treatment plan,they were taken continuously for 2 weeks as 1course.VAS reduction rate,VAS and NDI scores and TCM syndrome scores of the two groups were collected before treatment,1 week after treatment and 2 weeks after treatment,and the curative effect was analyzed.A total of 1 course was observed.Results:1.General information: Before treatment,there was no statistically significant difference in age and gender distribution between the two groups,indicating comparability.2.NDI,VAS score and efficiency: Between the two groups before treatment,1 week after treatment and 2 weeks after treatment,there were statistically significant differences in NDI,VAS and VAS reduction between the treatment group and the control group(P < 0.05),suggesting that both groups could effectively treat the Taiyang meridian headache syndrome of great occipital neuralgia,and there was no statistically significant difference between the two groups 1 week after treatment(P>0.05).Indicating that both groups achieved good efficacy in the treatment of great occipital neuralgia in the short term,but there were statistically significant differences in NDI,VAS,VAS reduction rate and effective rate between groups 2 weeks after treatment(P < 0.05),suggesting that the treatment group was better than the control group in improving the long-term effect of great occipital neuralgia.3.TCM syndrome scores and efficacy: Intra-group comparison between the two groups before treatment,1 week after treatment and 2 weeks after treatment showed statistically significant difference between the treatment group and the control group in improving TCM syndrome scores(P <0.05),suggesting that both groups could improve TCM symptoms of Taiyang meridian headache syndrome of occipital great neuralgia.The total effective rate of 1 week after treatment was statistically significant(P >0.05),indicating that both groups achieved good efficacy in the treatment of great occipital neuralgia in the short term,but the total effective rate of 2 weeks after treatment was not statistically significant(P <0.05),indicating that the treatment group has better long-term effect than the control group in improving TCM symptoms.4.Safety evaluation: There was no statistical significance in adverse reactions between the two groups(P>0.05),indicating that the drug in the two groups was safe in clinical use.Conclusion:In the treatment of Taiyang meridian headache syndrome of occipital great neuralgia,the prescription has a significant clinical effect.There is no significant difference between the Gabapentin treatment group and the Western treatment group in terms of improving Visual Analogue Scale(VAS),Neck Disability Index(NDI),and the curative effect of TCM syndrome.It can improve the headache related symptoms of patients and help them resume their daily life and work.Moreover,the curative effect of the treatment group after 2 weeks was significantly better than that after 1 week and the control group,and it was safe and reliable and could be applied clinically. |
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