Treatment Of Medium And Severe Cancer Pain With Local Radiofrequency Heat Therapy In Conjunction With A Subcutaneous PCA Pump

Objective: To observe the efficacy and safety of local radiofrequency thermotherapy combined with subcutaneous PCA pump for the relief of moderate to severe cancer pain.Methods: 90 patients with cancer pain were collected in this study.All patients were divided into 3 groups of 30 patients each via the random number table method.The groups included non-PCA pump(Oral Oxycontin group A),PCA pump(group P),and local radiofrequency thermotherapy combined with subcutaneous PCA pump(group H),a 2-week treatment course.The NRS score,titration success time,number of outbreak pain,and daily average drug dosage of patients in each group were observed and compared at each time point,as well as patient satisfaction,incidence of adverse reactions,quality of life score,and re-admission rate due to pain after 2 months of treatment.Following treatment,the data was sorted and statistically analyzed.Results:(1)NRS scores: NRS scores were significantly lower in groups P and H than in group A24 hours and 7 days after treatment(p<0.05).Group H was significantly lower than group A at 14 days after treatment(p<0.05),and there was no statistically significant difference between groups P and A(p>0.05).At all time points,there was no statistically significant difference in NRS scores between groups P and H(p>0.05).(2)Titration success time: The difference in titration success time(2 consecutive NRS scores ≤ 3)between group P and group H was not statistically significant(p>0.05),and both were significantly lower than group A(p<0.05).(3)Number of outbreak pain: The number of outbreaks of pain in the three groups was inversely related to time.At 24 hours,7 days,and 14 days after treatment,with the number of outbreak pain at each time point being A>P>H.Except for the difference in the number of outbreak pains at 24 hours after treatment between the H and P groups(p>0.05),all differences were statistically significant(p>0.05).(4)Average daily drug dose in groups P and H: With the exception of group H,where the average daily drug dose was lower at 14 days after treatment compared to 24 hours after treatment,the average daily drug dose was positively correlated with time at all points in all groups,and the dose in group H was significantly less than that in group P at 14 days after treatment,with a statistically significant difference(p<0.05).(5)Patient satisfaction rate:After 14 days of treatment: the patient satisfaction rate in group A was 70.0%,86.6% in group P,and 90.0% in group H.Patient satisfaction was significantly higher in group H than in group A,and the difference was statistically significant(p<0.05).(6)The incidence of adverse reactions: During the treatment period,none of the three groups experienced any serious adverse reactions.Groups P and H experienced significantly lower rates of nausea and vomiting than group A(p< 0.05),and group H experienced significantly lower rates of appetite loss than group A(p<0.05).There were no statistically significant differences between groups P and H in the prevalence of any adverse responses(p>0.05).(7)Quality of life scores:14 days after treatment,all groups experienced an increase in their appetite,mental,sleep,fatigue,daily life,and total scores;the differences were statistically significant(p<0.05);except for mental and fatigue,the differences between the scores of group P and group A were statistically significant(p<0.05);except for sleep and daily life,the differences between the scores of group H and group P were statistically significant(p<0.05).Appetite,mental,sleep,fatigue,daily life and total scores were all significantly higher in group H than in group A,and the differences were statistically significant(p<0.05).(8)Readmission rate due to pain after 2 months of treatment: After two months of treatment,there was a readmission rate for pain of 13(43.3%)in group A,6(20.0%)in group P,and 4(13.3%)in group H.The difference between group H and group A was statistically significant(p<0.05).Conclusion: Subcutaneous PCA pump can quickly relieve cancer pain,and when combined with local radiofrequency hyperthermia,they can further reduce the number of pain outbreaks,daily drug dose,and the incidence of adverse reactions,improve patient satisfaction rate and patients’ quality of life,and reduce readmissions due to pain.This study offered patients with a cost-effective and practical combination analgesic treatment while demonstrating the effectiveness and safety of local radiofrequency heat therapy in conjunction with subcutaneous PCA pump for analgesia.