| Objective: To observe the clinical curative effect of quadruple therapy(solid yuan moxibustion,fire needle,cupping,acupoint catgut embedding)on herpes zoster due to liver meridian stagnation heat based on the theory of strengthening vital qi to eliminate pathogenic factor.Methods: Sixty patients who met the research criteria of herpes zoster due to liver meridian stagnation heat were randomly divided into a treatment group and a control group,30 cases in each group.The patients in the treatment group were treated with Yuangu moxibustion,fire needle,and cupping combined with acupoint catgut embedding,once a week for one course.Patients in the control group were treated with filiform needle acupuncture,blood-letting puncture and cupping.Filiform needle acupuncture was performed once a day,for a course of 5 days,with two days’ rest before the next course.Bloodletting and cupping were performed once every other day until the herpes scabbed.Before each course of treatment,the efficacy of the two groups was evaluated according to the herpes zoster comprehensive efficacy score table,and the treatment was stopped when the cure standard was reached.Meanwhile,the treatment time was counted,and the patients who failed to meet the standard were allowed to continue the treatment,with the longest treatment lasting for four courses.The time to stop blister,scab and remove crust,the degree of pain after each course of treatment and four courses of treatment(visual simulation score),the change of comprehensive herpes score,and the incidence of postherpetic neuralgia(PHN)in the two groups were observed and recorded.Finally,the differences in clinical efficacy between the two methods were analyzed and compared.Results:1.Baseline data analysis: gender composition of patients in two groups(30 cases in the treatment group: 10 males(33.33%)and 20 females(66.67%);30 cases in the control group: 11 males(36.67%)and 19 females(63.33%);Age structure(treatment group: 49.67±9.04 years old,control group: 48.87±10.01 years old);Course distribution(treatment group: 4.33±1.58 days,control group: 4.20±1.63 days);VAS score(treatment group:8.87±1.07,control group: 8.83±1.12)and herpes complex score(treatment group: 20.63± 1.90,control group: 20.67 ± 1.88)before treatment;The differences were not statistically significant(P > 0.05),with comparability.2.Analysis of treatment results:(1)Analysis of blister stopping,scabbing and eschar removal scores: Comparison of treatment methods between the two groups showed that the blistering stopping(3.43±0.82days),scabbing(6.63±1.03 days),and eschar removal(11.80±1.19 days)in the treatment group were significantly better than those in the control group(5.27±1.26 days),scabbing(8.57±1.00 days),and eschar removal(14.60±1.55 days),with significant differences(P< 0.01).(2)VAS score analysis: after each course of treatment: intra-group comparison: the two groups were significantly reduced,the difference was significant(P < 0.01).Inter-group comparison: after one course of treatment,the value of the treatment group was(6.27±1.34)lower than that of the control group(7.30±1.47),and the difference was statistically significant(P < 0.05).After the second,third and fourth courses of treatment,the values of the treatment groups were(3.37±1.33,1.33±0.71 and 0.50±0.63),which were significantly lower than those of the control group(4.90±1.32,2.33±1.18 and 1.10±0.85),the difference was significant(P < 0.01).(3)Analysis of herpes comprehensive score: after each course of treatment,the scores were significantly reduced in both groups(both P < 0.01).Inter-group comparison: After the first,second,third and fourth courses of treatment,the values in the treatment groups were(12.83±5.03,7.33±5.09,3.17±3.23 and 0.67±1.21)significantly lower than those in the control group(15.43±4.86,10.70±5.60,6.20±5.24 and 2.43±3.69),and the differences were statistically significant(P < 0.05).(4)Comparison of clinical effects: The treatment cycle was significantly shortened in the treatment group,with four cured cases occurring after two courses of treatment.After four courses of treatment,the final results of clinical efficacy showed that the cure rates of the treatment group and the control group were 90.00% and 70.00%,respectively,and the difference was statistically significant(P < 0.05).(5)The comparison of PHN incidence rates:between the treatment group and the control group showed that the PHN incidence rates in the treatment group and the control group were 0.00% and 23.33%,respectively,and the difference was statistically significant(P < 0.05).Conclusion: Based on the theory of "strengthening vital qi to eliminate pathogenic factor",the quadruple therapy is applied for the treatment of herpes zoster due to liver meridian stagnation heat.It has significant advantages in improving the pain severity of patients,alleviating herpes symptoms,shortening treatment cycle,improving clinical cure rate and reducing the occurrence of postherpetic neuralgia,which is worthy of promotion. |
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