A Preliminary Study On The Distribution Of TCM Syndrome Elements In Cough Variant Asthma

ObjectiveThis paper is preliminarily explore the distribution law of TCM syndrome elements on cough variant asthma(CVA).It provides a basis for the objectification and standardization of TCM syndrome differentiation for this disease,and attempts to provide a useful reference for TCM clinical syndrome differentiation.Method1.Statistical method of syndrome elementsAccording to Professor Zhu Wenfeng’s "syndrome differentiation" in the "simplified measurement" method to identify the evidence,the specific method is as follows:(1)The symptoms and signs of the relevant evidence of the diagnosis of the weight of the calculation:the symptoms and signs of each case,"proof syndrome" in the "syndrome syndrome",check their diagnosis of the relevant evidence of the simplified metering weights.(2)The severity of the syndrome with disease or disease:complaints or illness,to(+)said,according to the weight of×1.5 measurement;moderate disease,according to the weight×1 measurement;disease light,to(-)said,weight×0.7 measured.(3)The total weight of calculation card:the patient’s symptoms and signs of each relevant evidence of the diagnostic metering weights were weighted sum(including minus the value)to calculate the total weight of the syndrome.(4)The diagnostic criteria for syndromes:reference to "evidence syndrome" in the relevant standards,generally take[20]100 as a general threshold,that is,the contribution of each symptom to the amount of evidence or more than[20],you can diagnose the corresponding evidence,and distinguish syndrome severity according to the sum of the weight,namely:Total weight<[14]70,the diagnosis of the card can not be established;The total weight in the[14]70～[20]100,the evidence is Ⅰ(first,lighter);The total weight in the[21]101～[30]150,the evidence is Ⅱ(two,obvious);Total weight>[30]150,the certificate is Ⅲ(three,serious).(5)To simplify the measurement method:first by syndromes of the relevant evidence of the weight of one by one registration,and then summed up the diagnostic value of the syndrome,and evidence to determine the diagnosis.2.Statistical processingAll the data collected in clinic were collated and audited,then the corresponding information was filled in the Excel software system.The patient-related symptoms and signs in the contribution of the statistics were determined,and then the corresponding syndrome elements were diagnosed by the syndrome diagnostic criteria.SPSS 20 statistical software was used to analyze and process the data.Statistical analysis of frequency was made on the general data of CVA patients,the distribution and combination of syndrome elements.Fisher’s Exact test was used to analyze whether there were differences in the distribution of pathological syndrome among different groups of CVA.The difference was statistically significant(P<0.05).The cluster analysis was used to analyze the syndrome elements.Result1.CVA in women patients more than men,the ratio of man to woman is 1:1.88.The onset of CVA is mainly between 18～44 years of age,accounting for 53.26%.Upper respiratory tract infections is the leading factors that induce or aggravate cough,accounting for 41.30%.The most common complication is allergic rhinitis which accounts for 21.74%.Cold air and odor irritation account for 61.97%in history of allergy.2.The frequency of lung is the highest in the syndrome of disease location,followed by the exterior;the pathological syndrome is mainly phlegm and yin deficiency,and the other is dampness and heat.3.The combination pattern of CVA,the main syndrome of disease location focuses on lung;lung and exterior is mostly seen in two disease location.The combination of pathological syndromes consists of single evidence,two evidence and three evidence.Single evidence accounts for the highest proportion,phlegm and yin deficiency appear relatively more frequently;phlegm and dampness is relatively common in two syndromes distribution;three combinations of syndromes is relatively scattered.According to the frequency of syndrome elements combination,the form is mainly single and two evidence.Lung and phlegm,lung and yin deficiency are common in two syndromes combination;lung,phlegm and dampness is mostly seen in three syndromes combination.4.According to the clustering analysis of syndromes,the common TCM syndromes of CVA are:phlegm-damp amassing in lung syndrome,wind-cold attacking the exterior syndrome,yin deficiency internal heat syndrome and qi-blood deficiency syndrome.5.The distribution of CVA syndrome elements didn’t differ in gender and age groups.The syndrome of disease location is mainly lung;phlegm and yin deficiency are mostly seen in pathological syndromes.Conclution1.The majority of adult CVA patients are women.The elderly population mainly in the young patients.The incidence of CVA is closely related to upper respiratory tract infection and allergic rhinitis,some patients are allergic to cold air and odor irritation.2.The syndromes of disease location mainly distribute in lung and exterior.The distribution of pathological syndromes is phlegm,yin deficiency,dampness and heat.3.The combination form of disease location syndromes is the most single syndrome.Phlegm and dampness is relatively common in the combination of pathological syndromes.Lung and phlegm,lung and yin deficiency are common pattern in two syndromes combination;lung,phlegm and dampness is mostly seen in three syndromes combination.4.The common TCM syndromes of CVA are:phlegm-damp amassing in lung syndrome,wind-cold attacking the exterior syndrome,yin deficiency internal heat syndrome and qi-blood deficiency syndrome.