Analysis Of The Relationship Between Hcy,ApoAI,ApoB And The Stability Of Carotid Artery Plaque In Patients With TIA

Objective: TIA is a kind of ischemic cerebrovascular disease,recurrent transient cerebral circulation ischemia is easy to progress for cerebral infarction,a serious threat to our country residents’ lives and health,disease,in recent years,its incidence increased along with the economic development,the social from all walks of life have already taken focus on its main causes atherosclerosis research is becoming more and more attention of cervical atherosclerotic plaque unstable plaque can easily lead to thrombosis or embolism,in particular,actively prevent the formation of unstable plaque,reduce the onset of TIA,can further reduce the occurrence of cerebral infarction of this subject is to explore the TIA patients with hcy apolipoprotein A1.Methods: 1.The object of study: choose between December 2017 and December2018 in mail he nan city first hospital neurology hospital treatment of 122 patients with TIA,and satisfy the onset age 35-85 years old;Improve the blood indexes were in the hospital 24 hours and neck vascular ultrasound examination;Comply with TIA definition of the American stroke association recommended guidelines2 implementation plan: take the retrospective study,the selected cases according to the result of the neck vascular ultrasound is divided into A plaque and B the plaque group(IMT normal,IMT thickening)two large groups,then A plaque group divided into unstable plaque group(mixed echo plaques,low echo plaques),stable plaque group(strong echo plaques)two groups.Collect patients’ age,sex,blood pressure and blood tests and other indicators.3data processing: Baseline data such as gender and age were compared between groups A and B and various biochemical indicators were compared between the two groups.Within group A,levels of various biochemical indicators of hcy apolipoprotein AI apolipoprotein B in the baseline data were compared between the unstable plaque group and the stable plaque group.Results: There was A statistical difference between group A and group B in age,indicating that the probability of carotid artery unstable plaque formation increased with age,and age was an independent risk factor.There was no statistically significant difference between the two groups in gender composition ratio,BMI,diabetes,hypertension,smoking and drinking.The level of apolipoprotein AI was lower than the latter,and the level of Hcy in group A was higher than that in group B.The generalbaseline data of the unstable plaque group in group A showed no statistically significant difference between the uric acid FIB DD apolipoprotein B apolipoprotein AI and the stable plaque group.The Hcy level in the unstable plaque group was significantly higher than that in the stable plaque group,and the level affected the stability of atherosclerotic plaque.Conclusions: Age,Hcy,apolipoprotein B,total cholesterol(TC),triglyceride(TG),and low-density lipoprotein(LDL)are risk factors for the formation of atherosclerotic plaques.Apolipoprotein AI has a protective effect on the formation of atherosclerosis.The higher the level of Hcy,the more unstable the atherosclerotic plaques are.