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Clinical Study Of Dingchuan Decoction,Xuanfu Dai Zhe Decoction And Montelukast Sodium In The Treatment Of Bronchial Asthma(Phlegm-heat Obstructing Lung Syndrome)in Children

Posted on:2021-01-13Degree:MasterType:Thesis
Country:ChinaCandidate:Z Z SuFull Text:PDF
GTID:2404330647955551Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Objective:Combined with modern medicine understanding of children asthma acute phase,and the basic theory of TCM,for support,explore the phlegm heat indicates the characteristics of pulmonary syndrome of TCM etiology and pathogenesis of infantile asthma,with xuan ti lung and stomach treatment of phlegm,using the prescription of Dingchuan decoction and Xuanfu daizhe powder,cutting joint Montelukast sodium chewable tablets for treatment,were observed before and after treatment with signs and symptoms and lung function improvement,as phlegm heat indicates pulmonary syndrome children asthma treatment provides a new train of thought.Method:A total of 60 children who met the western medicine diagnostic criteria and TCM syndrome differentiation criteria of phlegm-heat obstructing lung syndrome in children with bronchial asthma during the acute attack period were selected.The patients were randomly divided into treatment group and control group,with 30 cases in each group.The treatment group was treated with traditional Chinese medicine decoction(Dingchuan decoction and Xuanfudaizhe powder)combined with oral Montelukast Sodium Chewable Tablets,while the control group was treated with Chinese patent medicine(Xiaoer Feire Kechuan oral solution)combined with oral Montelukast Sodium Chewable Tablets.If the symptoms or signs of the two groups of children did not significantly relieve after the use of the above drugs,atomization inhalation(terbutaline sulfate atomization combined with budesonide suspension)could be used as needed for treatment,and The Times and days of use were recorded as required.Both groups were treated for 14 days.In the treatment of the first day,the third day,the seventh day and the 14 th day observed the symptoms and signs as well as the improvement of pulmonary function before and after the treatment.By using the software of statistical SPASS21.0 finally collected the clinical data for statistical processing and analysis,compare the curative effect of two groups of treatment plan,and objective evaluation of its clinical curative effect.Results:1.Comparison of disease efficacy:after two weeks of treatment,the treatment group have clinical cured 11 cases,14 cases were markedly effective,3 cases effective,ineffective in1,and the total effective rate was 96.55%;In the control group,have clinical cured 3 cases,13 cases were markedly effective,10 cases effective,3 no effect,and the total effective rate was 89.66%.Statistical analysis of the clinical efficacy of the treatment group and the control group showed that P<0.05,suggesting that the clinical efficacy of the treatment group was better than that of the control group.2.Comparison of the effective rate of total TCM syndromes : after 2 weeks of treatment,the treatment group have clinical cured 13 cases,14 cases were markedly effective,2 cases effective,ineffective in 0;In the control group,have clinical cured 1 cases,11 cases were markedly effective,15 cases effective,2 no effect.Data of the two groups were statistically analyzed and processed,P<0.05,suggesting that the treatment group had a better effect on total TCM symptoms than the control group.3.Intra-group comparison of each individual symptom: the intra-group comparison of each individual symptom before and after treatment in the treatment group and the control group was statistically significant(P<0.05),indicating the improvement of each individual symptom before and after medication in the two groups.4.Intergroup comparison of each single symptom: on day 3±1,day 7±1 and day 14,the comparison of scores of cough,wheezing,sputum and pulmonary wheezing between the treatment group and the control group showed P<0.05,with statistically significant differences,and the curative effect of each single symptom in the treatment group was higher than that in the control group.5.Comparison of remission time of main symptoms and pulmonary wheeze between the two groups: the remission time of cough,wheeze and pulmonary wheeze between the two groups was P<0.05.The remission time of the treatment group was significantly shorter than that of the control group,indicating that the therapeutic effect of the treatment group was better than that of the control group.6.Comparison of atomization inhalation frequency between the two groups: among the two groups,the number of atomization inhalation used by mild patients as needed was compared(P<0.05),while the number of atomization inhalation used by moderate patients was compared(P<0.05).The total number of atomization inhalation was compared between the two groups(P<0.05),indicating that the number of atomization inhalation in the treatment group was less than that in the control group.7.Comparison of lung function: the comparison of the improvement of lung function index(FEV1 as a percentage of the expected value)in the two groups after treatment was statistically significant,indicating that the improvement of lung function in the treatment group was better than that in the control group,with P<0.05.Conclusions:This study uses Dingchuan decoction,Xuanfu daizhe powder cutting combined Montelukast sodium chewable tablets to observe the acute onset of bronchial asthma in children.The basic etiology and pathogenesis of asthma in acute exacerbation are explained from the theory of ventilator lift and lung and stomach.The machine adopts the method of promoting lung and reducing qi,and eliminating phlegm by stomach has a remarkable clinical effect.Especially in terms of lung function,the improvement of lung function in the treatment group was better than that in the control group,which provided new ideas for the understanding and treatment of asthma,phlegm-heat obstructing lung syndrome of asthma,and also reflected the perfection of dialectical treatment of traditional Chinese medicine and precise treatment of western medicine.The combination of Chinese and Western fusion can achieve better therapeutic effect.
Keywords/Search Tags:Bronchial asthma in children, Phlegm-heat obstructs lung syndrome, And the stomach to dissolve phlegm, Promote lung qi, Clinical curative effect
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