Clinical Study Of Self-designed Jianpi Jiedu Decoction In The Treatment Of Cancer-related Fatigue In Patients With Digestive Tract Malignant Tumor

Objective: To study the clinical efficacy of self-designed jianpi jiedu decoction in the treatment of cancer-related fatigue in patients with gastrointestinal malignancies by analyzing multidimensional fatigue scale(MFI-20),KPS score,TCM syndrome score and peripheral blood.To explore the clinical application value of self-designed jianpi jiedu decoction in the treatment of cancer-related fatigue in patients with digestive tract malignant tumors.Methods: 78 patients included in the standard were divided into observation group and control group by random number table method.The observation group was treated with jianpi jiedu decoction combined with conventional symptomatic treatment,while the control group was only treated with conventional symptomatic treatment,with a course of treatment of 21 days.By observing the multidimensional fatigue scale(MFI-20),KPS score,TCM syndrome score and peripheral blood of the two groups before and after treatment,the treatment results of the two groups were compared,and SPSS21.0 statistical software was used for statistical processing to evaluate the efficacy of the self-designed jianpi jiedu decoction.Results: There was no significant difference in MFI-20,KPS,TCM syndrome score and peripheral blood between the two groups before treatment(p > 0.05).After 21 days of treatment: 1.In terms of clinical symptoms,the curative effect of TCM syndromes showed that the symptoms in the observation group such as fatigue,spontaneous sweating,loss of appetite,and loose stools were alleviated more obviously than those in the control group(p < 0.05);2.In terms of fatigue level,the multidimensional fatigue scale(mfi-20)score showed that the observation group was significantly lower than the control group in terms of total fatigue score,physical fatigue,mental fatigue and activity reduction(p < 0.05),and the observation group was more effective in reducingthe fatigue status of patients(p < 0.05).;3.In terms of survival status,KPS score showed that the improvement of life status in the observation group was better than that in the control group(p < 0.05).4.In terms of peripheral blood images,the indexes of hemoglobin,red blood cells and albumin in the treatment group were better than those in the control group(p < 0.05).Conclusion: The self-designed jianpi jiedu decoction in the treatment of cancer-induced fatigue,the results show that it can significantly alleviate the clinical symptoms of patients,reduce the fatigue of patients,improve patients’ peripheral blood indexes,improve the quality of life of patients,and good safety,worthy of clinical promotion.