The Clinical Observation For Treating Alopecia Areata With Qi-blood Deficiency Type By Yiqi Buxue Sheng Fa Tang Combined With Plum Blossom Needle

Objective: To observe the clinical efficacy of tutor’s empirical formula Yiqi Buxue Sheng Fa Tang with plum-blossom needle tapping in treating the alopecia areata with qi-blood deficiency type,discussing the mechanism of its treatment and the safety and stability of its curative effect,to provide theoretical basis for the promotion of Yiqi Buxue Shengfa Tang for treating alopecia areata with qi-blood deficiency.Method: All clinical data were collected between February 2016 and February 2017.Selecting the alopecia areata with qi-blood deficiency who were from the Dermatology Clinic of the Wuhan Traditional Chinese Medicine Hospital.All clinical data had selected strictly by the clinical diagnostic criteria.A total of 60 patients were included in this study.Among them,the treatment group was given tutor’s empirical formula Yiqi Buxue Sheng Fa Tang,of essential drugs:astragalus mongholicus 30 g,angelica sinensis 10 g,cassia twig 10 g,bighead atractylodes rhizome 10 g,saposhnikovia divaricata 6g,rhizoma zingiberis 6g,chinese-date 10 g,radices paeoniae alba 10g,ligusticum wallichii 6g,liquorice 6g,fushen 10 g,codonopsis pilosul 10 g,poria cocos 10 g,fructus aurantii 10 g,lignum millettiae 30 g,2 times/day,in the morning and Evening.The control group was given Bazhen tablets,of essential drugs:angelica,radix-codonopsis,radices paeoniae alba,atractylodes macrocephala,radix rehmanniae,poriacocos,Ligusticum wallichii,licorice.Oral.3-tablets once,3 times a day.Both two groups were combined with the external features of traditional Chinese medicine of plum-blossom needle tapping.Take 30 days as a treatment cycle.A total of 2-treatment cycles were observed in the entire research programme.First,recording the lesions of the two groups before treatment,then the scores of skin lesions at the end of 1 month and 2 months of treatment were compared with those before the treatment.Evaluating its clinical efficacy.We also observed the uncomfortable reaction during the whole course of the treatment and followed up on the recurrence of the disease after 3 months.Result: 1.After one month later,comparing the skin lesion scores of the two groups,the difference was statistically significant(P<0.05).The treatment group healed in 12 cases,8 cases had marked effect,7 cases were improved,3 had no effect,the total efficient is 66.67%,the control group healed in 5 cases,7 cases had marked effect,8 cases were improved,10 had no effect,the total efficient is 40.00%.The clinical effective rate of the treatment group was significantly higher than that of the control group,the difference was statistically significant.The results showed that the effect of treatment group was better than that of control group.2.After two months later,comparing the skin lesion scores of the two groups,the difference was statistically significant(P<0.05).The treatment group healed in 25 cases,2 cases had marked effect,2 cases were improved,1 had no effect,the efficient is 90.0%,the control group healed in 17 cases,3 cases had marked effect,5 cases were improved,5 had no effect,the total efficient is 66.67%.The clinical effective rate of the treatment group was significantly higher than that of the control group,the difference was statistically significant.The results showed that the effect of treatment group was better than that of control group.3.Following up the two groups of patients after three months,to observe the recurrence of the disease,2 cases of recurrence in the treatment group,8 cases of recurrence in control group,the difference of recurrence probability between the two groups was statistically significant(P<0.05).The results showed that the therapeutic effect of the treatment group was more lasting stability.4.During the course of diagnosis and treatment,3 cases of adverse reactions in the treatment group.They were manifested as stomach discomfort after taking medicine.After taking medicine after meals,these symptoms can be alleviated.2 cases of adverse reactions in the control group,including 1 case of mild diarrhea,and another case was performed uncomfortable when knocking on the head by plum blossom needle,but could be alleviated after rest.Conclusion 1.Yiqi Buxue Sheng Fa Tang with plum-blossom needle tapping in treating the alopecia areata with qi-blood deficiency type,which has the advantages of good clinical diagnosis and treatment,low recurrence and less adverse events and small side effects,worthing to popularize and apply widely in clinic.2.Yiqi Buxue Shengfa Tang is better than Bazhen tablet in treating alopecia areata with qi-blood deficiency type.