Clinical Characteristics And Treatment Of Cerebral Salt Wasting Syndrome

Objective: To analyze the clinical characteristics and the effect ofrehydration therapy of central nervous system diseases, combined with cerebralsalt wasting syndrome in patients, improve clinical understanding of thecerebral salt wasting syndrome.Methods:collecting43cases of central nervous system disease withcerebral salt wasting syndrome, divided into2groups according to serumsodium to reduce the degree of: in group Ⅰ: serum sodium <130mmol/L and>120mmol/L,; group Ⅱ: serum sodium <120mmol/L. Systmactly observingand analyzing patients’ gender, age, medical history, time of onset,hyponatremia (<130mmol/L) time and time of onset interval returned tonormal by the treatment of hyponatremia (>130mmol/L and remained withinthe normal range3days) time,summarize the clinical characteristics of patientswith cerebral salt wasting syndrome and the efficacy of rehydration therapy.Results: The central nervous system disorders caused by cerebral saltwasting syndrome mostly occurred10days after the illness; hyponatremiasodium supplement treatment recovery time, in group Ⅰ was significantly lessthan the II group (P <0.05); II group of patients given hypertonic salinetreatment, the serum sodium returned to normal time and significantly less thansaline treatment only; dehydration therapy in patients with clinical systems,serum sodium returned to normal time.Conclusion: Cerebral salt wasting syndrome caused by hyponatremia,mostly in the disease after6to10days;with the lower of sodium concent-ration and the longer the time required rehydration therapy; sodium concentr-ation is low, given hypertonic saline therapy was superior to saline; Clinical dehydration therapy can affect the correction of hyponatremia.