| Objective:Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) refers to the hypersecretion of antidiuretic hormone (ADH) leading to water retention by all reasons., and its main representation is dilutional hyponatremia. SIADH is a kind of tumorous emergency with insidious course, and its most common reason is small cell lung cancer (SCLC). This article discusses the diagnosis of SIADH and differential diagnosis with hyponatremia by hypovolemia to diagnose and treat SCLC patients with SIADH.Methods:12 patients suffered from SCLC with SIADH were enrolled in the First Affiliated Hospital of Dalian Medical University, Oncology, from January 2000 to December 2009, there were 3 patients with mild hyponatremia (120mmol/l |