| Background:Essential Hypertension (EH) is a common disease, in the clinical report cardiovascular system.In recent years the morbidity is increasing at home and abroad gradually.Currently there are many researches about TCM syndrome type in EH,which still shows a diversified trend,and hasn't been formed a unified standard. As the smallest part of TCM syndrome type in diagnose, syndrome's element have unique advantages in solving miscellaneous syndrome type,and have positive significance for traditional medicine diagnosis and treatment of EH. At present the clinical research reports in syndrome's elements of EH and the correlation between the syndrome's elements and biochemical indexes in studies is still rarely reported.Objective:To observe the distribution characteristics of TCM syndrome elements about grade 2 EH patients in different ages or totally, and analyze the correlation between syndrome's elements and physiochemical index. To discusses traditional susceptible factors in EH patients. Methods:The information of 326 Grade 2 hypertension patients was collected, from June,2009 to January,2011, in zhongshan hospital with Xiamen university affiliated and Xiamen Chinese Medicine Hospital. By using the method of syndrome element dialectic, and in combination with TCM syndrome differentiation of symptoms grading standards,we elected by the quantified integral and statistical treatment, and found that the distribution features of every syndrome elements. To divide the patients into youth (18-40 years old), a middle-aged grouP (41-65 years old) and the elderly group (66-85 years old), and study the the the distribution features of every syndrome elements in different ages,and analyse the correlation between syndrome's elements and ALT,AST,BUN,Agâ…¡,UA and so on.Results:1. The distribution characteristics of syndrome's elements for Grade 2 hypertension patient in Xiamen.The order of disease location of Grade 2 EH was liver>spleen>kidney>lung>others>, in which liver was the predominant (222cases,68.1%),by statistical inspection, the cases of liver had significant differences with other groups. The common empirical syndrome's elements were sputum>damp,>blood stasis> yang excess>wind>fire>others, and in which the sputum, damp and blood stasis were more frequent than other goups(The sputum 182cases, 55.8%;dampl71 cases,52.5%;blood stasis 150cases 46.0%).The haven't significant differences with each other.(P>0.05),and had significant differences with other syndrome's elements groups respectively(P<0.01).The distribution characteristic of deficiency syndrome's elements were yin deficiency>qi asthenia> yang deficiency>blood deficiency> jing difficiency, among which the case of yin deficiency were the most one (149cases, 45.7%).Yin deficiency had significant differences with other syndrome's elements(P<0.01).2. The distribution characteristics of syndrome's elements in different ages for Grade 2 EH patients.In youth group the liver element was predominant,by statistical inspection, this disease location of syndrome's element had significant differences with other group(P<0.01). The most common empirical syndrome's element was yang excess,which had significant difference with other grousps(P<0.01). The deficiency syndrome's elements in this group hadn't significant difference with each other.In middle-age group,spleen was predominant in disease location of syndrome's elements,and the sputum and damp were the most cases in common empirical syndrome's elements,which hadn't significant differences with each other(P>0.05). In elderly group,yin deficiency and blood stasis was most important element.3. The distribution features of miscellaneous syndrome type in for Grade 2 EH Patients.The disease location of miscellaneous syndrome's element was liver and kidney>liver and spleen>spleen and kidney>heart and spleen>heart and kidney>others,in which the rate of liver and kidney was the most than other groups(78cases 23.9%).In common empirical syndrome's elements,the order was sputum and damp>sputum and blood stasis>wind and excess>wind and sputum>sputum,damp and blood stasis>wind,sputum and blood stasis.The sputum and damp was primary position(sputum and dampwas 122cases 37.4%;sputum and blood stasis 97cases 29.8%),which hadn't difference with each other. In the distribution features of common empirical and deficiency syndrome's elements for Grade 2 EH patients, the qi and yin deficiency was predominant(62cases 19.0%).The miscellaneous syndrome type containing deficiency and common empirica was yin deficiency,blood stasis and sputum,(75cases 23.0%)4. The correlation of Physical indexes and syndrome's elements:The Agâ…¡and ET had positive relation with the disease location syndrome's element of liver(P<0.05).TC,LDL-C,TG, Agâ…¡and ET had positive relation with syndrome's element blood stasis,sputum and damp. (P<0.05). UA had positive relation with syndrome's element qi defficience and yang defficience.(P<0.05),and had negative relation with yin defficience.Conclusion: 1 In the subjects of Grade 2 EH in Xiamen, The disease location syndrome's element of liver was predominant, sputum,damp,blood stasis and yin deficiency were the main characteristics.2 Different group of ages of Grade 2 EH had different distribution features.in syndrome"s element.3 The main miscellaneous syndrome's elements of Grade 2 EH was liver and kidney,sputum and damp,qin and yin deficiency,yin deficiency and blood stasis and sputum.4 The syndrome's elements had some correlation with TC,TG,LDL-C,HDL-C and so on. |
PDF Full Text Request