Clinical Research, Self-blood Therapy Of Chronic Urticaria

ObjectiveIn recent years, the study about chronic urticaria was madegreat progress。The incidence rate of chronic urticaria is high,and chemical drug treatment is effective but easy to relapse。Self-blood-injection-acupuncture, one special way ofacupuncture, is super to chemical drug treatment for itspersistent effect and little side effect。In thispaper, 56 caseswith chronic urticaria were treated bySelf-blood-injection-acupuncture, compared with another38, treated with Loratadine, then the effect ofSelf-blood-injection-acupuncture is evaluated objectively,thereby we can provide evidence to clinic therapy for chronicurticaria。Metheods94 patients with chronic urticaria were collected from thedermatology department in Hubei hospital of TCM from 2005.3 to2006.2. All patients were classic chronic urticaria, excludedSLE, pemphigus, dermtomyositis, autoimmune diseases and otherallergy disease。No antihistamine has been used in recent 2 weeks,and immunosupressant, corticosteroids drugs affecting immunefunction has not been used in recent 2 months. They were dividedinto two groups randomly: A. rhe therapeutic group 56 cases weretreated by Self-blood-injection-acupuncture; B. The control group38 cases were treated with Loratadine, 10 mg qn po. We recordeditch, number, scale of rash, relapse rate and SSRI, And then, the therapeutic effects of two groups were compared basedon their changes.ResultsIn group A, the totally effective rate was 94.64%; and itwas 97.36% in group B. There is no significant difference shownbetween the two groups in the rates of effectiveness (P＞0.05). Thesignificant difference about the integral of symptoms was shownstatistically before and after treatment in both groups(P＜0.05).There was significant difference betweenSelf-blood-injection-acupuncture and Loratadine In reduction ofrelapse rate. (P＜0.05)ConclusionSelf-blood-injection-acupuncture and Loratadine areboth effective ways of treatment to chronic urticaria. ButSelf-blood-injection-acupuncture is superior to Loratadine inthe clinical efficacy.