| Purpose:By observing the clinical effect of internal administration of Chinese medicine plus acupoint application therapy and simple internal administration of Chinese medicine on insomnia patients with deficiency of heart and spleen,comparing the improvement of the two treatments on sleep quality,sleep latency,wake times,TCM symptoms and so on,exploring the reasons for the difference between internal and external treatment combined with simple internal administration of Chinese medicine in the treatment of insomnia patients with deficiency of heart and spleen,and exploring the basis of its efficacy.To provide reference for the clinical application of treating insomnia with deficiency of heart and spleen.Material and method:A total of 60 insomnia patients who met the criteria for case scheduling were collected from the encephalopathy clinic of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from November 2021 to November2022.They were randomly numbered into observation group and control group at a ratio of1:1.All patients in control group were treated with Guipi decoction as the main empirical formula,one dose was divided into three times,one week was a course of treatment,lasted for4 weeks,and the total treatment days were 28 days.On this basis,the observation group was treated with Yongquan point acupoint application treatment,which was applied before going to bed every night and taken off the next morning.The application time was controlled within8 hours as far as possible.5 days of acupoint application was a course of treatment,and 2days of rest was taken after each course of treatment,a total of 4 courses of treatment,and the total treatment days were 28 days.After the course of treatment,the evaluation criteria for insomnia efficacy in Guiding Principles for Clinical Research of New Chinese Medicines were used to evaluate the clinical efficacy.Pittsburgh Sleep Index Scale(PSQI)and sleep latency and wake times recorded in the sleep diary were used to evaluate the sleep quality of the patients.The symptoms of heart and spleen deficiency were evaluated by TCM symptom score scale.All adverse events and adverse reactions occurred during the treatment were recorded.SPSS22.0 software was used for data analysis,and then the therapeutic effects of the two groups were compared.Results:A total of 60 cases of insomnia patients with deficiency of heart and spleen were observed in this study.During the study,1 case fell off in the observation group and the control group respectively.1 case fell off in the observation group due to skin discomfort after application and could not be continued treatment,and 1 case fell off in the control group due to inability to adhere to medication.Finally,58 cases were included in statistical analysis,29 cases in the observation group and 29 cases in the control group.1.Comparability analysis of general data and baseline data of cases:Before treatment,gender,age,course of disease and other general data and relevant baseline data(sleep latency,wake times,PSQI scores and total scores between groups and TCM syndrome scores between groups)were compared between the two groups,and the results showed that p > 0.05,the differences were not statistically significant and were comparable.2.Intra-group data analysis after treatment:Sleep latency,wake times,PSQI scores and total scores,as well as TCM syndrome before and after treatment in two groups.All scores and total scores decreased to different degrees,and the results showed that p < 0.05,the difference was statistically significant.3.Data analysis between groups after treatment:After treatment,there were no significant differences in PSQI scores related to sleep disorders and daytime disorders between the two groups(p > 0.05),but the differences were statistically significant in sleep time,sleep time,sleep quality,sleep efficiency and total score(all meeting p < 0.05).There were significant differences in sleep latency and wake times in patients’ sleep diaries(p < 0.05).There were differences in the scores of TCM symptom accumulation table for insomnia,fatigue and total scores(p < 0.05),while there was no statistical significance in the comparison of other symptoms between groups(p > 0.05).4.Comparison of effective rate between the two groups after treatment:After the course of treatment,the total effective rate of the observation group was 93.10%,and the total effective rate of the control group was 82.76%,p < 0.05 after statistical analysis,the difference was statistically significant.Conclusion:1.Internal administration of Hui-Pi decoction can improve the sleep quality of insomnia patients with deficiency of both heart and spleen,as well as palpitation and forgetfulness,lack of energy and food,dizziness,pale face,tired limbs,distension and loose stool and other TCM syndroms of deficiency of both heart and spleen.2.Acupoint application therapy can shorten sleep latency,reduce the number of awakenings,improve sleep quality and efficiency,prolong sleep time and improve the symptoms of insomnia and palpitation.3.The overall clinical effect of acupoint application therapy on insomnia with deficiency of heart and spleen is better than that of Guipi decoction,which can be further tried in clinic. |
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