| Objective: To evaluate the clinical efficacy and safety of Zhang zhitong Neiyi prescription in the treatment of chronic pelvic pain of endometriosis with qi stagnation and blood stasis syndrome,and to provide reference data for clinical treatment of chronic pelvic pain of endometriosis.Methods: A total of 70 patients who met the inclusion criteria of this study were selected and randomly divided into observation group and control group according to random number table method from January 2021 to March 2022.The observation group was given different analgesic prescription,and the control group was given Sanjie Analgesic capsule.The efficacy and safety of the observation group were evaluated by comparing the VAS score of pain,TCM symptom score,QUALITY of life EHP-5 score,blood CA125,Maximum diameter of ovarian cyst and safety indexes of the two groups before and after treatment.Results: After treatment,VAS score,TCM syndrome score,QUALITY of life EHP-5 score,blood CA125 and Maximum diameter of ovarian cyst were statistically significant differences between the 2 groups before and after treatment(P < 0.05),and observation indexes between the 2 groups were statistically significant differences(P < 0.05),and the observation group was better than the control group.The total effective rate of the two groups in improving pain was90.91% and 82.35%,respectively.The total effective rate of the two groups in improving TCM syndrome was 93.94% and 88.24%,respectively,and the differences were statistically significant after statistical analysis(P < 0.05).Conclusion:Both groups can improve chronic pelvic pain and TCM syndromes caused by EMs,and can also improve the quality of life of patients,and the effect of different analgesic prescription is more significant than sanjie Analgesic capsule.In addition,the effect of sanjie Zhentong capsule on improving blood CA125 and Maximum diameter of ovarian cyst is better than than that of sanjie Zhentong capsule. |
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