Analysis Of Nutritional Status And Clinical Correlation In Patients With Chronic Obstructive Pulmonary Disease

Objective:This study aims to evaluate the nutritional status ofpatients with acute exacerbation of chronic obstructive pulmonary disease（AECOPD）through nutritional risk screening,analyze the risk factors of malnutrition in AECOPD patients and their clinical relevance,so as to arouse clinicians’attention to the nutritional status of AECOPD patients.Methods:Relevant data of patients who met the inclusion criteria were collected:（1）General data:gender,age,BMI,smoking history and other relevant information;（2）Clinical data:pulmonary function index,blood gas analysis parameters,biochemical nutritional index and inflammatory index,NRS2002 score,length of hospital stay,number of acute exacerbations and complications in the previous year.Results:Results:A total of 140 AECOPD patients were included in this study,including 77（55%）in the normal nutrition group and 63（45%）in the malnutrition group.1.There was no statistically significant difference in the gender,smoking history,complications（hypertension,type 2 diabetes,pulmonary infection,coronary heart disease,respiratory failure）between the patients in the normal nutrition group and the malnutrition group（P>0.05）,but there were statistically significant differences in the number of acute exacerbations in the previous year,age,BMI,and length of hospitalization（P<0.05）.2.CRP,FEV1/FVC,FEV1%pred,ALB,TP,PAB and Pa O2 in the patients with normal nutrition were higher than those in the patients with malnutrition（P<0.05）,however,there was no significant difference in PCT,Scr,PH and Pa CO2（P>0.05）.3.The NRS2002 score was positively correlated with age,the number of acute exacerbations in the previous year,and CRP（r=0.235,0.258,0.173,P<0.05）,while negatively correlated with BMI,FEV₁%pred,FEV₁/FVC,ALB,TP,PAB,Pa O₂（r=-0.650,-0.612,-0.652,-0.307,-0.251,-0.234,-0.466,P<0.05）.The results of binary multivariate logistic regression analysis showed that age,BMI,FEV₁/FVC were independent factors related to the nutritional status of AECOPD patients,and the difference was statistically significant（P<0.05）.Conclusion:1.Malnutrition is common in AECOPD patients.Of the 140patients in this study,63 were in the malnutrition group,accounting for45%.2.Malnutrition of AECOPD patients will prolong hospital stay,Poor lung function.3.The older the age,the more times of acute exacerbation last year,the higher the CRP,and the higher the NRS2002 score of AECOPD patients.4.Age,BMI,FEV₁/FVC and other factors are related to the nutritional status of AECOPD patients.