Clinical Observation Of Jiawei Gualou Xiebai Banxia Decoction Combined With Conventional Western Medicine In Treating AECOPD Syndrome Of Phlegm And Stasis In The Elderly

OBJECTIVE: To observe the clinical efficacy of Jiawei Gualou Xiebai Banxia decoction combined with conventional western medicine in the treatment of in treating AECOPD Syndrome of phlegm and stasis in the Elderly.METHODS: A total of 74 inpatients meeting the criteria were included and randomly divided into control group and treatment group with 37 cases in each group.The control group was treated with conventional western medicine,and the treatment group was additionally treated with Gualou Xiebai Banxia decoction on the basis of conventional Western medicine treatment.The course of western medicine was 14 days,and the course of traditional Chinese medicine was 10 days.The change of White blood cell count,Neutrophil percentage,C-reactive protein,Procalcitonin,D-dimer,Fibrinogen,Partial pressure of Oxygen,Partial pressure of carbon dioxide,Forced expiratory volume in one second,Forced expiratory volume in one second / Forced vital capacity,TCM symptoms and the sign scores were recorded before and after treatment in both groups.SPSS26.0 was used to statistically process the data to evaluate the efficacy of the two groups of patients.RESULTS:(1)After treatment,the levels of WBC,N%,CRP and PCT in the treatment group decreased more significantly than that in the control group,the difference was statistically significant(P<0.05),indicating that the treatment group was better than the control group in improving the level of inflammation;(2)After treatment,the levels of D-D and FIB in the treatment group decreased more significantly than that in the control group,the difference was statistically significant(P<0.05),indicating that the treatment group was better than the control group in improving coagulation function;(3)After treatment,Pa O2 level increased and Pa CO2 level decreased more significantly in the treatment group than in the control group,the difference was statistically significant(P<0.05),indicating that the treatment group was better than the control group in promoting lung ventilation,relieving hypoxia and reducing carbon dioxide level.(4)After treatment,the level of FEV1 in the treatment group increased more significantly than that in the control group,the difference was statistically significant(P<0.05),indicating that the treatment group was better than the control group in improving lung ventilation and promoting lung function.(5)After treatment,the scores of sputum volume,chest tightness,wheezing,tongue quality and rales in the treatment group decreased significantly compared with that in the control group,with statistical significance(P<0.05),indicating that the improvement of sputum volume,chest tightness,wheezing,tongue quality and rales in the treatment group was due to the control group.(6)After treatment,the TCM symptoms,signs and total scores of the two groups were significantly lower than before treatment,the difference was statistically significant(P<0.05),indicating that the treatment group was better than the control group in improving the overall symptoms and signs of patients;(7)After treatment,0 patients in the control group were clinically controlled,effective for 10 days,effective for 19 days,ineffective for 6 patients,and the total effective rate was82.86%;After treatment,3 patients in the control group were clinically controlled,the effect lasted for 19 days,effective for 11 days and ineffective for 3 patients.The total effective rate was 91.67%.The difference between the two groups was statistically significant(P<0.05),and the curative effect of the treatment group was better than that of the control group.(8)After treatment,there was no significant difference in FEV1/FVC,cough and complexion claw and nail scores between the two groups(P>0.05),indicating that there was no difference between the treatment group and the control group in improving the level of FEV1/ FVC,relieving cough and complexion claw and nail.CONCLUSIONS: The Jiawei Gualou Xiebai Banxia decoction Combined with conventional western medicine can significantly improve the clinical symptoms of elderly patients with phlegm blockage and blood stasis syndrome AECOPD,and play a positive role in reducing inflammation,improving hypercoagulability,reducing the risk of thrombosis,improving lung ventilation,and promoting lung function.