| Objective:Under the guidance of the theory of chronic disease and collaterals,chronic disease and blood stasis in traditional Chinese medicine,erjiu Decoction was used to treat chronic cough with phlegm-heat and blood-stasis syndrome in children,and its clinical efficacy and safety were observed and evaluated.Methods:Sixty children with chronic cough who were dialectically diagnosed as phlegm-heat and stasis syndrome were collected in the tutor’s clinic and divided into two groups(control group and treatment group),with 30 cases in each group.The treatment group was given Erjiu Decoction,and the control group was given Anerling granule(Jinha Tibetan medicine).The treatment course was one week.According to the self-made Children chronic cough Phlegm heat stasis lung Syndrome Score Table,the symptom changes of the two groups were quantified before and after treatment and a database was established.SPSS 26.0 software was used for data analysis to objectively evaluate the clinical efficacy and safety of Erjiu Decoction in treating children with chronic cough(phlegm,heat and stasis of lung syndrome).Results:The actual cases included in this study were 30 in the treatment group and 30 in the control group.Curative effect analysis: treatment group: cured 1 case,accounting for 3.33%,marked effect 19 cases,accounting for 63.33%,effective10 cases,accounting for 33.33%,ineffective 0 cases,accounting for 0.00%,total effective rate 100%;Control group: cured 0 cases,accounting for 0.00%,obvious1 case,accounting for 3.33%,effective 20 cases,accounting for 66.66%,ineffective 9 cases,accounting for 30.00%,the total effective rate was 70.00%;Chi-square test was used,P < 0.001,the curative effect of the two groups were different,and the curative effect of Erjiu Decoction was better than that of Anerling granule.T test showed that P < 0.001.Erjiu Decoction was superior to Anerling in improving the main symptoms of cough,phlegm and runny nose.T test was used to show that P=0.250,indicating that there was no significant difference between erjiu Decoction and Anerling granule in improving secondary symptoms.T test was used to compare the changes of the total symptom score of the two groups,and P < 0.00 was obtained,indicating that erjiu Decoction had better effect than Anerling granule in improving the clinical symptoms of chronic cough in children with phlegm-heat stasis syndrome.No adverse events occurred during the treatment,and the safety evaluation was level 1.Conclusion:Erjiu Decoction in the treatment of phlegm-heat stasis lung syndrome of chronic cough children,can significantly improve the clinical symptoms,good clinical efficacy,high safety,has clinical value,worthy of promotion. |