Investigation And Study On The Cognition Of Rational Drug Use Of Lipid-regulating Therapy By General Practitioners In Wuhan

Background and objective: Dyslipidemia is one of the common chronic diseases in community residents.As an important part of primary care,general practitioners provide grass-roots management services for patients with dyslipidemia in the community.The rate of reaching the standard of blood lipids largely depends on the rational use of lipid-regulating drugs by general practitioners.Therefore,through the method of questionnaire survey,this study takes the general practitioners in Wuhan as the research object to deeply understand the cognitive status of general practitioners on the rational use of drugs in lipid-lowering therapy and its related influencing factors.the purpose of this study is to provide reference for standardizing the drug use of general practitioners and the management of blood lipids in residents.Methods: This study adopts the method of combining theoretical research with empirical research.Through the method of literature research,the relevant treatment guidelines and academic papers about the application of lipid-regulating drugs at home and abroad were collected,and the literature was studied.Through the questionnaire survey,to understand the cognitive status of Wuhan general practitioners on the rational use of drugs and its related factors,and according to different levels of medical units,the influencing factors were analyzed by Poisson regression.Results:1.There were significant differences in general practitioners’ education,learning and access to medical information between the community health service center and the tertiary general hospital(P < 0.05).There were no statistical differences in gender,age,professional title,participation of clinical pharmacists,working years of general practice,the number of patients per day in outpatient service,and the proportion of dyslipidemia in the group of patients(P > 0.05).2.In terms of the selection of rational drug use for dyslipidemia,the question with the highest correct rate was the ninth question on the time of drug use,which was answered correctly in 123 cases(89.1%).The lowest correct rate was the seventh question on the intensity of different lipid-lowering drugs,which was answered correctly in 42 cases(30.4%).And there were differences in the scores of general practitioners in the selection of lipid-regulating treatment and rational use of drugs between community health service centers and tertiary general hospitals(P < 0.05).3.In the sample of general practitioners in community hospitals,the scores of general practitioners were taken as dependent variables,and the variables in the results of univariate analysis were analyzed by Poisson regression analysis.the results showed that the scores of general practitioners with learning times of 0,1 and 2 were lower than those of community general practitioners with learning times of 3 or more times in the past year(P<0.001,RR=0.592,95%CI:0.519-0.677)、(P<0.001,RR=0.626,95%CI:0.530-0.741)、(P<0.001,RR=0.701,95%CI:0.576-0.852).Compared with general practitioners with more than 60 patients per day,general practitioners with 30 to 60 patients per day had lower scores(P<0.05,RR=0.824,95%CI:0.709-0.957).4.In the sample of general practitioners in tertiary hospitals,the scores of general practitioners were taken as dependent variables,and the variables in the results of univariate analysis were analyzed by Poisson regression analysis.the results showed that the general practitioners with the proportion of dyslipidemia ≤ 25% had higher scores than those with dyslipidemia of 25%-50% and 50%-75%(P<0.001,RR=1.418,95%CI:1.180-1.704)、(P<0.001,RR=1.589,95%CI:1.320-1.912).Conclusion:The cognitive level of general practitioners in the central urban area of Wuhan for the rational use of lipid-lowering drugs is generally low,especially reflected in the cognition of the corresponding action intensity of different doses of lipid-regulating drugs.Among them,the cognitive level of general practitioners in community health service centers on the rational use of lipids is lower than that of general practitioners in tertiary general hospitals.We can pertinently carry out the study of topics related to dyslipidemia and increase the practical opportunities for young doctors to contact patients with dyslipidemia to improve the cognitive level of general practitioners on the rational use of drugs in lipid-regulating therapy.