| ObjectiveTo explore the correlation between traditional Chinese medicine(TCM)syndrome differentiation and VFA,muscle mass and function in elderly patients with type 2 diabetes mellitus(T2DM),and to provide reference for TCM clinical diagnosis and treatment of elderly T2 DM by collecting and analyzing clinical data of elderly T2 DM patients.MethodsFrom March 2022 to January 2023,127 patients with diabetes who visited the Endocrinology Department of Fujian University of Traditional Chinese Medicine affiliated People’s Hospital were selected as subjects according to the inclusion criteria.Basic information and clinical symptoms of the subjects were collected,and TCM syndrome differentiation was determined based on TCM diagnostic criteria.VFA was measured and muscle mass,strength,and function were evaluated.Glucose and lipid metabolism,as well as liver and kidney function,were also tested.The distribution of TCM syndrome differentiation in elderly T2 DM patients was analyzed,and the relationship between TCM syndrome differentiation and VFA,muscle mass and function was analyzed using statistical software.Results1.General information:(1)A total of 127 patients were included in this study,with 66 males(51.97%)and 61females(48.03%).The median age was 70 years(68,74)for males and 69 years(67,72)for females,with a male-to-female ratio of 1.08:1.There was no statistically significant difference in the distribution of TCM syndrome differentiation between different genders(P>0.05).(2)The age of the 127 patients included in this study ranged from 65 to 80 years old.From the age group analysis,patients between 65 and 70 years old had the highest number.There was a statistically significant difference in the distribution of age groups between different TCM syndrome differentiations(P<0.05).(3)Among the 127 patients included in this study,43(33.86%)had a disease duration of0-5 years,which was the most common.There was no statistically significant difference in disease duration between different TCM syndrome differentiations(P>0.05).(4)Among the 127 patients included in this study,106(83.46%)engaged in low-intensity activities.There was no statistically significant difference in the distribution of activity intensity between different TCM syndrome differentiations(P>0.05).2.Distribution of TCM Syndrome Types: Among 127 elderly T2 DM patients,the distribution of TCM syndrome types was mainly Qi-Yin deficiency syndrome,with a total of60 cases(47.25%),followed by phlegm-dampness obstructing syndrome with 30 cases(23.62%),Yin-Yang deficiency syndrome with 19 cases(14.96%),heat injuring fluid syndrome with 10 cases(7.87%),and liver-kidney Yin deficiency syndrome with 8 cases(6.30%).3.Comparison of TCM Syndrome Types and Clinical Treatment:(1)There was a statistically significant difference in calf circumference among all syndrome types(P<0.1),and the calf circumference of the phlegm-dampness obstructing syndrome group was higher than that of the liver-kidney Yin deficiency syndrome group(P<0.1).(2)There was a statistically significant difference in maximum grip strength among all syndrome types,and the grip strength of the heat injuring fluid syndrome group was greater than that of the Yin-Yang deficiency syndrome group(P<0.1).(3)There was a statistically significant difference in time to complete five sit-ups among all syndrome types,and the time required for the heat injuring fluid syndrome group to complete five sit-ups was shorter than that of the liver-kidney Yin deficiency syndrome group(P=0.087<0.1).(4)There was a statistically significant difference in BMI among all syndrome types,and the difference between the phlegm-dampness obstructing syndrome and the heat injuring fluid syndrome and liver-kidney Yin deficiency syndrome was statistically significant(P<0.05).The BMI value of the phlegm-dampness obstructing syndrome group was higher than that of the heat injuring fluid syndrome group,and the liver-kidney Yin deficiency syndrome group had the lowest BMI value.There was a statistically significant difference in BMI value between the liver-kidney Yin deficiency syndrome group and the Yin-Yang deficiency syndrome group(P<0.05),and the BMI value of the Yin-Yang deficiency syndrome group was higher than that of the liver-kidney Yin deficiency syndrome group.(5)There was a statistically significant difference in waist-height ratio among all syndrome types(P<0.05),and the waist-height ratio of the Yin-Yang deficiency syndrome group was the highest,followed by the phlegm-dampness obstructing syndrome group,the Qi-Yin deficiency syndrome group,the heat injuring fluid syndrome group,and the liver-kidney Yin deficiency syndrome group.4.Results of Logistic Regression Analysis: There was a correlation between BMI and calf circumference and the occurrence of heat injuring fluid syndrome(P<0.05);there was a correlation between waist-height ratio and the occurrence of liver-kidney Yin deficiency syndrome(P<0.05).Conclusion1.Among the 127 elderly T2 DM patients included in this study,the most common TCM syndrome type was Qi-Yin deficiency,followed by phlegm-dampness obstructing syndrome,Yin-Yang deficiency syndrome,heat injuring fluid syndrome,and liver-kidney Yin deficiency syndrome.2.There was no significant correlation between TCM syndrome types and visceral fat area in the 127 elderly T2 DM patients included in this study.3.This study found that there was a correlation between TCM syndrome types in T2 DM patients and BMI,calf circumference,and waist-height ratio,all of which can be used as objective references for TCM syndrome differentiation in T2 DM.Among them,low BMI and thin calf circumference were identified as risk factors for heat injuring fluid syndrome,while low waist-height ratio was identified as a risk factor for liver-kidney Yin deficiency syndrome. |
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