Correlation Study Of Family History And Gestational Diabetes Mellitus

·Objective: To explore the characteristics of insulin therapy selection,dosage,blood glucose,weight change,pregnancy complications,fetal birth pattern,and perinatal outcome in Gestational diabetes(GDM)patients with family history of diabetes 2(FHD),Methods: 399 patients with gestational diabetes admitted to the hospital from January2022 to December 2022 were selected as the study subjects.According to whether they had a family history of diabetes,the patients were divided into a family history group(89cases)and a family history free group(310 cases).The family history group was divided into a paternal group(35 cases),a maternal group(38 cases)and diabetes patients(16cases)according to the condition of both parents,The fasting blood glucose,1h blood glucose,2h blood glucose,saccharification and various biochemical indexes of the two groups of patients,and the differences between the two groups of pregnancy complications and neonatal complications and neonatal weight.Results:1.The diet and exercise control rate of blood sugar in gestational diabetes mellitus is high;2.Patients in the FHD group were more likely to use insulin for blood glucose control than patients without a family history(P< 0.05);3.Compared with the non-FHD group,there was a statistical difference in the use of short-acting insulin between the two groups(P< 0.05);4.Glycosylated hemoglobin,OGTT-1h blood glucose and OGTT-2h blood glucose in FHD group were higher than those in non-FHD group(P< 0.05);The preconception body weight and weight change of FHD group were lower than those of non-FHD group(P<0.05).Conclusion:1.GDM patients with FHD need clinical nutrition guidance and proper exercise in the early pregnancy,strictly control weight,regularly measure blood glucose,and use insulin intervention treatment if necessary.2.For GDM pregnant women with a clear family history,giving short-acting insulin according to their blood glucose can be more effective in raising vigilance for pregnant women with FHD.It is recommended to start monitoring blood glucose at an early stage,and start intervention treatment as soon as possible once abnormal blood glucose is found,so as to reduce the probability of adverse perinatal outcomes.