Comparative Study On Inflammation Index Of Different Severity And Different Treatment Methods In Emergency Trauma Patients

OBJECTIVE: The purpose of this article was to explore the changes in peripheral blood inflammatory indexes in injured and ill patients before receiving treatment and after receiving surgical treatment by analyzing the baseline information and inflammatory indexes of clinical injured and ill patients from January 1,2016 to December 31,2021,and taking into account the actual situation.METHODS: In this study,regression grouping was used to screen eligible patients from 186 injured and sick patients according to ISS criteria,and three groups were divided into minor,moderate and severe injuries according to their injuries and diseases,and then their indicators were analyzed.RESULTS: After systematic investigation and study,we found no significant differences(P>0.05)in the basic information and peripheral blood clinical indicators of the three groups of subjects,including but not limited to age group,gender,length,weight,heart rate,hypotension,temperature,causative cause and injury type,which indicated that the data of the three groups of subjects were similar and well balanced when compared.The results of comparing peripheral blood inflammatory indicators in injured subjects with different degrees of injury showed that the median leukocyte level was greater in the critically injured group(19.79)than in the severely injured(16.84)and mildly injured(10.74);the neutrophil level was higher in the critically injured group(14.56)than in the severely and mildly injured groups;the percentage of neutrophils was greater in the critically injured group > the mildly injured group > the severely injured group;calcitoninogen,interleukin 6,and C-reactive protein were higher in the critically injured group than in the mildly injured group,The levels of calcitoninogen,interleukin 6 and C-reactive protein were greater in the critically injured group than in the severely injured group and the mildly injured group.The remaining indicators did not show significant differences.After comparison,we found that there were significant changes(P<0.05)in the levels of leukocytes,neutrophils,percentage,interleukin 6,C-reactive protein,and calcitoninogen in the casualties who underwent surgery after surgical treatment.In particular,these indices were significantly higher in the critically reorganized casualties than in those in the severe and mild groups.When the cross-sectional comparison was made among the three groups,the differences in the magnitude of changes of the above indexes at 1 day and 7 days after surgery were not statistically significant(P>0.05).Conclusions: 1.Age,gender,BMI,underlying disease,temperature at admission,heart rate,height,weight,type and cause of trauma in emergency trauma casualties had no effect on the assessment of trauma severity.2.After the study,it was found that the three groups of subjects had statistically significant changes in leukocytes,neutrophils,neutrophil ratio,calcitoninogen,IL-6 and CPR;therefore,combining the above inflammatory indexes combined with ISS scores will provide an important basis for more accurate diagnosis of subject’s victimization.3.Among surgical casualties,the critical injury group and the severe injury group with early surgical intervention had the same effect of improving the inflammatory response caused by trauma as the mild injury group.