Clinical Observation On The Intervention Of Ba Duan Jin On Anxiety And Depression In Patients With Primary Sjogren’s Syndrome

1 Purpose Through a clinical study on the intervention of Baduanjin in primary Sjogren’s syndrome patients with anxiety and depression,the efficacy of Baduanjin in treating pSS patients with anxiety and depression was analyzed,opening up new ideas for clinical treatment.2 Methods68 patients with pSS who met the experimental criteria of this study were randomly divided into a control group(34 cases)and an experimental group(34 cases).week.The pain VAS score,dry mouth VAS score,eye dryness VAS score,fatigue VAS score,anxiety and depression self-rating scale,quality of life scale,parotid gland ultrasound,ESSPRI score,ink absorption test,and saliva flow rate were recorded in the two groups of patients.Through statistical analysis,evaluate the clinical curative effect of Baduanjin on pSS patients with anxiety and depression.3 Results 3.1 The effect of Baduanjin on the VAS score of pSS patients with anxiety and depression Compared with the control group,VAS scores of fatigue,dry eyes,and dry mouth in the treatment group had significant reduction at 8、12 weeks,and the Pain VAS scores of the treatment group at 12 weeks had significant reduction(P<0.05).Compared with before treatment,the treatment group: VAS scores of dry eyes and dry mouth at 4 、 8 、 12 weeks of treatment had significant a reduction,the fatigue VAS score was significantly abated at 8 weeks and 12 weeks post-therapy,and the Pain VAS score was significantly reduced at 12 weeks post-therapy(P<0.05),the VAS scores of dry eyes,fatigue,dry mouth,and Pain at 12 weeks of treatment were reduced(P<0.05) 3.2 Effect of Baduanjin on SAS in pSS patients with anxiety and depression Compared with the control group,the SAS score of the treatment group had significant reduction at 4,8,and 12 weeks,(P<0.05).Compared with before treatment,the SAS scores of the treatment group had significant reduction,at 4,8,and 12 weeks(P<0.05);the SAS scores of the control group had significant reduction at 8,12weeks(P<0.05). 3.3 Effect of Baduanjin on SDS in pSS patients with anxiety and depression Compared with the control group,the SDS score of the treatment group had a significant reduction at 4,8,and 12 weeks(P<0.05).Compared with pre-treatment,the SDS scores of the treatment group had significant reduction at 4,8,and 12 weeks(P<0.05);the SDS scores of the control group had significant lower at 8,12 weeks(P<0.05). 3.4 Effect of Baduanjin on SF-36 in pSS patients with anxiety and depression Compared with control group,the treatment-group’s scores of SF-36 had significant promotion at 8 、12 weeks(P<0.05).Compared with before treatment,the SF-36 score of the treatment group had significant increased at 4、 8 and 12 weeks(P<0.05),and the SF-36 score of the control group had significant promotion at 12 weeks(P<0.05).3.5 Effect of Baduanjin on parotid ultrasound in pSS patients with anxiety and depression Compared with the control group,there difference was no significant(P>0.05).Compared with before treatment,the ultrasound score of Parotid gland in the treatment group had significant decreased(P<0.05),and the ultrasound score of parotid gland in the control group had significant decreased(P<0.05). 3.6 Effect of Baduanjin on ESSPRI in pSS patients with anxiety and depression Compared with control group,the ESSPRI score of the treatment group had significant reduction(P<0.05).Compared with pre-treatment,the scores of the treatment group had significant decreased at 4 weeks,8 weeks,and 12 weeks(P<0.05),the differences in the control group were not significant(P>0.05). 3.7 The effect of Baduanjin on the ink absor Ption test results of pSS patients with anxiety and depression Compared with the control group,there was no significant difference in the ink absor Ption test of the treatment group(P>0.05).Compared with before treatment,the results of ink absor Ption test in the treatment group increased significantly(P<0.05),while the difference in the control group was not significant(P<0.05). 3.8 Effect of Baduanjin on saliva flow rate in pSS patients with anxiety and depression Compared with control group,the salivary flow rate of the treatment group was significantly increased(P<0.05).Compared with pre-treatment,the salivary flow rate in the treatment group was significantly improved(P<0.05),but the difference in the control group was not significant(P>0.05). 3.9 Effect of Baduanjin on laboratory indicators of pSS patients with anxiety and depression It was no significant difference in blood routine,liver and kidney function,IgM,IgA,IgG,ESR,hs-CRP persensitivity between the two groups(P>0.05).4 ConclusionFor patients with Sj(?)gren’s syndrome accompanied by anxiety and depression,regular practice of Baduanjin can significantly improve the anxiety and depression status of pSS patients,and can also enhance the quality of life,dry mouth,dry eyes,fatigue,pain and other symptoms of patients,and can add the tear fluid of patients,Salivation,is a therapy worth promoting.