| Objective:To clarify the epidemiology of serum 25(OH)D3levels in the hospitalized elderly,and its correlation with thyroid function parameters and other factors.To investigate whether the serum 25(OH)D3 level is a potential early warning indicator of thyroid dysfunction in the elderly,and to provide relevant evidence for whether vitamin D supplementation can prevent and treat thyroid diseases.Methods: A total of 227 elderly inpatients aged ≥ 65 years in the Second Xiangya Hospital were recruited.A questionnaire survey was conducted on the research subjects,and data such as physical examination and laboratory examination was collected.The relationship between serum 25(OH)D3 levels and thyroid function parameters and thyroid diseases was analyzed.Results:(1)The serum FT4 levels of elderly women were higher than that of elderly men,and the serum 25(OH)D3 levels of elderly women were lower than that of elderly men;(2)The prevalence of vitamin D deficiency and insufficiency in the elderly population was68.72% and 26.43%,respectively;(3)The prevalence of vitamin D deficiency in elderly women was higher than that in elderly men;(4)In the elderly population,the proportions of patients with subclinical hypothyroidism,hypothyroidism,subclinical hyperthyroidism and hyperthyroidism were 26.43%,10.13%,14.10% and 6.17%,respectively;(5)There was no seasonal difference in the levels of serum FT3,FT4,TSH,TPOAb and TGAb in the elderly;(6)The serum 25(OH)D3 levels in the elderly were not correlated with the serum TSH,FT4,TPOAb,and TGAb levels,and the serum 25(OH)D3 levels were positively correlated with the serum FT3 levels;(7)There was no significant correlation between serum 25(OH)D3 levels and the risk of subclinical hypothyroidism,hypothyroidism,subclinical hyperthyroidism and hyperthyroidism in the elderly population.Conclusion:1.Serum 25(OH)D3 levels are positively correlated with serum FT3 levels,but not with serum TSH,FT4,TPOAb and TGAb levels in hospitalized elderly population in China;2.Serum 25(OH)D3levels are not associated with thyroid diseases including hypothyroidism,subclinical hypothyroidism,hyperthyroidism and subclinical hyperthyroidism;3.Vitamin D supplementation may not prevent and treat thyroid diseases. |
