Fluid Co-loading Therapy After Spinal Anesthesia And Damage Control Resuscitation In Cesarean Section With Pernicious Placenta Previa

Objective:To investigate the application value of fluid co-loading therapy after spinal anesthesia and damage control resuscitation(DCR)in cesarean section with pernicious placenta previa.Methods:Retrospective analysis of 40 puerperae diagnosed with pernicious placenta previa in the obstetrics department of The First Bethuen Hospital of Jilin University,and the patients were divided into the observation group and the control group according to the anesthesia management method,20 patients in each group.The observation group was treated with fluid co-loading therapy and damage control resuscitation,and the control group with no special anesthesia management.In both groups,spinal anesthesia was administered before delivery of the fetus and general anesthesia was administered after delivery of the fetus.The intraoperative blood loss,infusion volume,body weight,blood transfusion volume,urine volume,operation time,hemoglobin difference and platelet difference before and after surgery,post-operative APTT,PT,Fib and Hct values in the two group.The neonatal Apgar score at 1min and 5min and the p H,Pa O2,Pa CO2 from blood gas analysis were compared between the two groups.Results:1.There was no statistically significant difference in age,gestational week,body weight,intraoperative bleeding,urine volume,blood transfusion,fluid transfusion,and duration of surgery between the two groups(P > 0.05).2.The difference in hemoglobin(Hb)before and after surgery between the two groups was statistically significant(P < 0.05);the difference in platelets before and after surgery was not statistically significant(P > 0.05).3.There was no statistically significant difference in postoperative APTT,PT,Fib and Hct in the two group(P > 0.05).4.The differences in 1 min,and 5 min Apgar scores between the two groups of neonates were not statistically significant(P > 0.05),There was no statistically significant difference in the p H,Pa O2,Pa CO2 from blood gas analysis between the two groups.Conclusions:Fluid co-loading therapy and damage control resuscitation can significantly reduce the loss of red blood cells in women with pernicious placenta previa during surgery,and effectively protect the blood’s formed components.It doesn’t affect maternal coagulation function and has no adverse effects on the newborn.