Arterial Stiffness Acute Changes Following Aerobic Exercise In Males With Different Blood Pressure Levels

Objectives To investigate the effects of acute aerobic exercise on arterial stiffness in male with different blood pressure levels.Methods This cross-sectional study utilized data for 1200 males aged 20-49 years from the Kailuan study cohort who participated in the fifth National Fitness Monitoring project.The brachial–ankle pulse wave velocity（b-a PWV）was measured as an index of peripheral arterial stiffness.Measurements were carried out before and immediately after cycling exercise.A multifactorial logistic regression model was used to analyze the factors affecting the change in b-a PWV before and after cycle ergometer exercise in the total population and in people with and without hypertension.Linear regression models were used to evaluate group changes in hemodynamic parameters post-exercise.We performed several sensitivity analyses to assess the robustness of our findings.First,we excluded participants with diabetes mellitus,which is associated with a high ba PWV and is a potential risk factor for arterial stiffness.To reduce the effect of the interval duration,we also conducted another sensitivity analysis by excluding participants with an interval duration between measurements greater than the 95%quantile（26.7 minutes）.Results A total of 940 participants（621 in the non-hypertensive group and 319 in the hypertensive group）aged 36.82±7.76 who completed a twice-quantitative cycle ergometer exercise and measure of b-a PWV at both the baseline and immediately after exercise were included in this study.In the general population,age,drinking,HR changes from baseline comparisons,hypertension,and VO₂max were all risk factors affecting the change in b-a PWV,so as non-hypertension.In the hypertensive participants,HR changes from baseline comparisons was a risk factor.The b-a PWV was decreased after acute aerobic exercise in the non-hypertension and hypertension groups（β:-40.29[95%confidence interval[CI]:-47.72～-32.86]vs.β:-20.45[95%CI:-31.32～-9.58]cm/s）.Participants without hypertension showed a greater decrease in b-a PWV（β:-19.84[95%CI:-33.83～-5.84]cm/s）than participants with hypertension（P=0.001）.Conclusions Aerobic exercise had an acute positive effect on arterial stiffness.This study provides evidence of a greater reduction in arterial stiffness in individuals without hypertension than in those with hypertension.Figure 1;Table 16;Reference 110...