| Objective: To observe the clinical efficacy of Tendon and Bone Injury Formula on thoracolumbar compression fractures after PVP through a randomized controlled trial,to analyze and explore the efficacy of Jing Gu Shang Formula in improving symptoms such as postoperative residual pain and functional impairment and preventing recurrent fractures after PVP,to assess its effectiveness in shortening the recovery time and improving postoperative rehabilitation,to provide clinicians with relevant experience and methods for the treatment of postoperative residual symptoms of thoracolumbar compression fractures after PVP and for rapid postoperative rehabilitation,and to provide new ideas for in-depth research on the combined Chinese and Western medicine treatment of postoperative rehabilitation of osteoporotic vertebral compression fractures.Methods: Sixty inpatient cases who met the relevant diagnostic and treatment criteria for thoracolumbar compression fractures and completed PVP for thoracolumbar compression fractures from January 2022 to October2022 in Ruikang Hospital,affiliated to Guangxi University of Chinese Medicine were selected.The patients were randomly divided into 30 cases each in the experimental group(postoperative conventional treatment + Jing Gu Shang formula)and the control group(postoperative conventional treatment)according to the randomized control principle.VAS,ODI,TCM symptom score scale and efficacy scale were recorded before treatment,on the first day after surgery,1 week after surgery,2 weeks after surgery,3months after surgery and follow-up in both groups;CRP was checked by blood sampling before surgery,on the day after surgery and 1 week after surgery;the height of the anterior margin of the vertebral body before surgery,1 day after surgery and 3 months after surgery,and the re-fracture of the vertebral body adjacent to surgery.The relevant research work strictly followed the design protocol to ensure the authenticity,accuracy and completeness of the relevant statistical data.The statistical aspects of this pilot study were processed and analysed using SPASS22.0.A two-sided test was performed for statistical aspects,with P<0.05 indicating that the data were statistically different and statistically significant.Results:1.58 cases were involved,all from the Department of Spine of Rui Kang Medical Department,Guangxi University of Traditional Chinese Medicine.There were 29 cases in the observation group and 29 cases in the observation group.The enrolled cases strictly followed the scientific experimental design criteria and met the inclusion and exclusion criteria.The observation and control groups met the selection and exclusion criteria.The preoperative general electronic medical record information data and baseline of the patients in the test and control groups were not statistically significant(P > 0.05)and were comparable.2.In terms of pain relief,there was a statistically significant decrease in VAS scores between preoperative and postoperative day 1 within the two patient groups,with a statistically significant difference between the two groups(P < 0.05).The VAS scores of patients in both groups decreased at 1week,2 weeks and 3 months after surgery,and the difference between the two groups was statistically significant(P < 0.05).There was no statistical difference in VAS scores between the two groups at 1 day postoperative and 3months postoperative(P>0.05);the comparison of VAS scores of low back pain between the two groups at 1 week and 2 weeks postoperative showed statistically significant results(P<0.05),and the pain relief effect of the test group was better than that of the control group.3.In terms of CRP values,the two groups showed a decreasing trend between preoperative and postoperative day 1 and day 7,with a statistically significant difference between the two groups(P < 0.05).There was a statistically significant difference(P < 0.05)in the decrease in CRP values between the two groups 1 week after surgery,and the anti-inflammatory effect of the test group was better than that of the control group.4.In terms of motor function,the ODI scores of patients in both groups showed a decreasing trend before surgery,1 day after surgery,1 week after surgery,2 weeks after surgery and 3 months after surgery,and the difference was statistically significant(P < 0.05).There was no statistically significant difference between the two groups in terms of ODI scores before and 1 day after surgery(P>0.05),but there was a statistically significant difference between the two groups in terms of ODI scores at 1 week,2 weeks and 3months after surgery(P<0.05),indicating that the test group was better than the control group in improving postoperative functional impairment and promoting recovery of motor function.5.Regarding the height of the anterior border of the injured spine,there was an improvement in the height of the anterior border of the injured spine in both groups before surgery compared to 1 day after surgery,and the data were statistically different(P < 0.05);there was no statistical difference between the two groups when comparing the height of the anterior border of the injured spine in 1 day after surgery and 3 months after surgery(P > 0.05).Demonstrated that there was no statistical difference in the height of the anterior margin of the injured vertebrae between the two samples of the test and control groups at 1 day postoperatively and 3 months postoperatively(P >0.05);.6.In terms of adjacent vertebral re-fracture,no significant difference was seen between the test group and the control group in terms of adjacent vertebral re-fracture after 3 months first than(P > 0.05).7.In terms of TCM symptom scores,after 3 months of treatment,the effective rate of TCM symptomology was 86% in the test group and 55% in the control group,with a statistical difference between the two groups(P <0.05).The overall efficacy of the treatment was 93% in the test group and 83%in the control group after 3 months of treatment,with a statistical difference between the two groups(P < 0.05).Conclusion:(1)PVP surgery can restore the height of the vertebral body,while relieving pain symptoms and improving the functional impairment of the low back.(2)The Jing Gu Shang Formula can improve the symptoms of postoperative pain and dysfunction as well as the overall efficacy of PVP,accelerate the progress of rehabilitation,improve the effect of postoperative rehabilitation,provide relevant experience and methods for rapid postoperative rehabilitation,and provide new ideas for the in-depth study of the combined Chinese and Western medicine treatment of postoperative rehabilitation of osteoporotic vertebral compression fractures. |
