Study On The Correlation Between Blood Lipid Level And Endometrioid Carcinoma

Objective:At present,domestic and foreign studies on the correlation between lipid level and endometrial cancer have not been unified.The purpose of this study was to further elucidate the correlation between lipid levels and endometrioid carcinoma.Method: A total of 180 patients with endometrioid cancer who were initially diagnosed in the Affiliated Hospital of Chifeng University from 2019 to 2022 were collected through the electronic medical record system.A total of 180 patients were included according to the screening criteria.The age composition ratio of the study group was used as matching condition,and 180 patients admitted for benign endometrial lesions(endometrial polyps)during the same period were randomly selected as the control group.SPSS software was used to analyze the general information of the data,relevant test indicators,incidence of abnormal indicators and chronic diseases.All tests were statistically significant with(P<=0.05).Results:1.The study group and the control group were similar in age of onset,age of menarche,pregnancy times,childbirth times and proportion of menopause,with no statistical significance(P>0.05).The Body Mass Index was significantly different from the control group(P<=0.05).2.The incidence of chronic diseases such as obesity,hypertension and diabetes in patients with endometrioid cancer was significantly higher than that in the control group,and the differences were statistically significant(P<=0.05).3.The levels of serum TC,TG and LDL-C in the study group were higher than those in the control group,and the difference was statistically significant(P<=0.05).There was no significant difference in serum HDL-C level between the two groups(P>0.05).4.The incidence of TC≥5.2mmol/L,TG≥1.7mmol/L,LDL-C≥3.4mmol/L,FPG≥6.1mmol/L and BMI≥24kg/m2 in the study group was higher than that in the control group,and the differences were statistically significant(P<=0.05).There was no significant difference in the incidence of HDL-C<1.0mmol/L in the study group compared with the control group(P>0.05).5.In the subgroup with normal body mass index and no chronic complications,there were no statistically significant differences in age of onset,age of menarche,number of pregnancies,number of births and proportion of menopause in the endometrioid cancer subgroup(P>0.05).6.The levels of serum TC and LDL-C in endometrial carcinoma subgroup were significantly higher than those in control group,and the difference was statistically significant(P<=0.05).There was no significant difference in serum TG and HDL-C levels between the control group and the control group(P>0.05).7.The incidence of serum TC≥5.2mmol/L and LDL-C≥3.4mmol/L in endometrioid carcinoma subgroup was higher than that in control group,and the difference was statistically significant(P<=0.05).There was no significant difference in the incidence of serum TG≥1.7mmol/L and HDL-C<1.0mmol/L in endometrioid carcinoma subgroup compared with the control group(P>0.05).Conclusions: Elevated serum TC and LDL-C levels are closely related to the occurrence of endometrial carcinoma,and TG levels may be related to the occurrence of endometrial carcinoma.However,affected by body mass index and chronic complications.There was no significant correlation between HDL-C level and endometrioid carcinoma.The incidence of dyslipidemia is high in endometrioid carcinoma.Overweight,obesity,hypertension,and abnormal glucose metabolism are more common in patients with endometrioid cancer.