The Relationship Between The Contents Of Serum Mineral Element&the Abnormal Glucose, Lipid Metabolism In Ningxia Rural Residents

Objective To investigate the relationship between the content of serummineral element and the abnormal glucose, lipid metabolism in Ningxia ruralresidentsMethods A cluster random sampling method was adopted. Baselineinformation of native rural residents from the Yaergou village and Zhaosivillage in Guyuan sanying town, and the Young Tan Village and Shaba Wan Villagein Qingtongxia city were collected. The sample size of baseline was3391. Afterhaving the consents from respondents,1612blood samples of respondents werecollected to detect the blood parameters. According to the diagnostic criteriaproposed by the IDF (International Diabetes Federation) in2005, the abnormalglucose and lipid metabolism were diagnosed. The actual sample size for patientswith abnormal glucose metabolism and patients abnormal lipid metabolism were169respectively.According to case control study, the relationship between thecontents of serum mineral elements and the abnormal glucose and lipid metabolismwere analyzed by Partial correlation and Logistic regression statisticalanalysis method.Results The first part was the relationship between the abnormal glucose metabolism and mineral elements: There were statistically significant indifferent contents of Li, Mn Ni, Fe, Cu, Zn, Cr, K, Mg and Ca in serum betweenthe group of abnormal glucose metabolism and the control group. Except Cu,the contents of other elements in the group of abnormal glucose metabolism werelower than those in the control group. Significantly negative correlation（r=-0.215，P=0.021）was found between the contents of P in serum and the glucoselevel at fasting status. Li, Ca and Mg were the protective elements in theabnormal glucose metabolism, while Al was the risk elements.The second part was the relationship between the abnormal lipidmetabolism and mineral elements: There were statistically significant indifferent contents of Mn, Ni, Sn, Zn, Cr, K, Mg and Na in serum between the groupof abnormal lipid metabolism and control group, and the content of each elementin the group of abnormal lipid metabolism was lower than that in the controlgroup. It showed significantly negative correlation between the contents of Mnand Zn in serum and LDL-C（r=-0.319，P=0.003；r=-0.226，P=0.038）, so was thecontents of Mg in serum and LDL-C（r=-0.304，P=0.005）, the contents of Ca andNa in serum and LDL-C（r=-0.215，P=0.048；r=-0.352，P=0.001）, the content ofK in serum and LDL-C（r=-0.217，P=0.046）. Significantly negative correlationwere found between the content of P in serum and TC, TG, HDL-C（r=-0.349，P=0.000；r=-0.349，P=0.001；r=-0.360，P=0.001）,so was the content of Cr in serum andTG（r=-0.311，P=0.004）, the content of K in serum and TC（r=-0.241，P=0.026）.Sr, Zn and Na were the protective elements in the abnormal lipid metabolism,while Al was the risk elements.Conclusions There is difference in the contents of some mineralelements between the group of the abnormal glucose and lipid metabolism andcontrol group. The protective elements are Li, Ca and Mg in the abnormal glucose metabolism, and Sr, Zn and Na in the abnormal lipid metabolism, while riskelement is Al in both abnormal glucose and lipid metabolism.