| Purpose:1.To evaluate the clinical effect of combining Mongolian and Western medicine in the treatment of dilated cardiomyopathy.2.To provide reference for future research on the treatment of dilated cardiomyopathy by combining Mongolian and Western medicine.Method:From December 2021 to December 2022,60 patients with DCM diagnosed in the Internal medicine Department of Mongolian Medicine Center,Inner Mongolia Minzu University--Grade II or Grade III patients with Jirudian Habenheyi partial hyperactivity syndrome in Mongolian medicine were selected and randomly divided into the treatment group receiving Mongolian medicine and the control group receiving conventional Western medicine,with 30 patients in each group.The control group was treated with spirolactone tablets 20 mg,Shakubactril valsartan sodium tablets 100 mg,metoprolol tartrate tablets 25 mg,and Tolasemide tablets 5mg.The treatment group was treated with Xin-II 3g,Alataneles-8 powder 3g,Imanzhanggu-3 decoction 3g,and Shaosa-7 flavor 6g pills in conventional western medicine.The course of the disease lasted for 8weeks.After treatment,the improvement of symptoms,the total clinical effective rate and the efficacy index were compared between the two groups.And observe the influence on blood routine,liver function,kidney function,urine routine,ion and other safety indexes.Results:1.In the treatment group,14 cases were effective,13 cases were effective,3 cases were ineffective,and the total effective rate was 90%.In the control group,12 cases were effective,13 cases were effective,5 cases were ineffective,and the total effective rate was80%.After statistical analysis,the curative effect of the treatment group was significantly higher than that of the control group(P < 0.05).2.By comparing the Mongolian medicine syndrome scores of the two groups before and after treatment,statistical analysis showed that the Mongolian medicine syndrome scores of the treatment group and the control group were decreased after treatment(P <0.05),and compared between the two groups,the Mongolian medicine syndrome scores of the treatment group were improved more significantly than that of the control group(P <0.05)).3.The LVEF values of the two groups before and after treatment were compared,and the statistical analysis showed that the LVEF values of the treatment group and the control group were increased(P < 0.05),and the comparison between the two groups after treatment was statistically significant(P < 0.05),indicating that the two groups of drugs can improve the EF value.There was statistical difference between the two groups(P <0.05),indicating that the curative effect of the treatment group was better than that of the control group.4.The LVEDd value of the two groups before and after treatment was compared,and statistical analysis showed that the intra-group comparison of the two groups after treatment was statistically significant(P < 0.05),indicating that the two groups of drugs can reduce the LVEDd value.There was statistical difference between the two groups(P <0.05),indicating that the curative effect of the treatment group was better than that of the control group.5.Comparing the plasma NT-pro BNP level of the two groups of patients before and after treatment,statistical analysis after treatment in the two groups of comparison were statistically significant(P < 0.05),indicating that the two groups of drugs can reduce the plasma NT-pro BNP level.After treatment,there was statistical difference between the two groups(P < 0.05),there was statistical difference between the two groups,indicating that the curative effect of the treatment group was better than that of the control group.6.The improvement of cardiac function was compared between the two groups: in the treatment group,there were 4 cases of obvious effect,24 cases of effective,2 cases of ineffective.The total effective rate was 93.33%,5 cases were effective,20 cases were effective,5 cases were ineffective,the total effective rate was 83.33% after comparison between groups P < 0.05,there was statistical significance.The above data indicated that both the treatment group and the control group could improve cardiac function,and the curative effect of the treatment group was superior to the control group.7.Safety assessment during treatment showed no abnormalities and no adverse events.Conclusion:1.The combination of Mongolian and Western medicine and syndrome differentiation in the treatment of dilated cardiomyopathy can obviously improve the clinical effect.2.The combination of Mongolian and Western medicine in the treatment of dilated cardiomyopathy can decrease plasma NT-pro BNP level,LVEDd value and increase LVEF value.3.Mongolian medicine can improve the heart function and clinical symptoms of patients with cardiopathy,so as to enhance their quality of life.And in the course of treatment,no obvious side effects occurred,so it is a very safe drug,worthy of further research,application and promotion. |
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