| Objective:By collecting and analyzing Duodenal Ulcer(DU)cases,and studying correlation between endoscopic performance,TCM syndrome and physical constitution,for the purpose of establishing innovative diagnosis and treatment ideas,providing theoretical support for clinical disease prevention and treatment,and better promote the development of Traditional Chinese Medicine.Method:Investigate and analyze the data of 476 patients who meet the case selection criteria,observe and record their demographic characteristics,clinical symptoms,tongue and pulse,gastroscope reports,etc.The TCM syndrome type and physical constitution type of the patients were analyzed and determined,and the final data were analyzed by SPSS 25.0.Results:1.A total of 476 patients were included in this study,including 317 male patients(66.60%)and 159 female patients(33.40%);the average age was 53.0±13.0 years old,and the middle-aged group had the largest incidence.2.DU mostly occurred in the ball(97.69%),mostly single(78.36%),and the most common were round-shaped(79.83%),with the diameter <1.0cm being the most common,accounting for 89.50%.3.The distribution of TCM syndrome types of DU patients:spleen-stomach weakness(cold)syndrome was the most common,followed by spleen-stomach dampness-heat syndrome and stomach yin deficiency syndrome was the least.In addition to the spleen-stomach weakness(cold)syndrome,the spleen-stomach dampness-heat syndrome and liver-stomach stagnation-heat syndrome were more common in male patients,and liver-stomach stagnation-heat syndrome and liver-stomach disharmony syndrome were more common in female patients,the spleen-stomach dampness-heat syndrome was the most common in young patients,and the spleen-stomach weakness(cold)syndrome was the most common in middle-aged and elderly patients.There was no correlation between TCM syndrome types and ulcer location,size,number,bleeding and ball deformation(P>0.05),in addition,there were significant differences between syndrome types and ulcer surface coating,congestion and edema of surrounding mucosa,peripheral mucosal erosion(P<0.05);those with thick yellow coating on the surface of the ulcers were more common in the spleen-stomach dampness-heat syndrome,and those with thin white coating were commom in the spleen-stomach weakness(cold)syndrome;mucosal erosion was more common in spleen-stomach dampness-heat syndrome and liver-stomach stagnation-heat syndrome.4.The main physical constitution type of DU were yang-deficiency constitution,dampness-heat constitution,qi-deficiency constitution,qi-depression constitution,and phlegm-dampness constitution.Dampness-heat constitution was the most common in male patients,and yang-deficiency constitution was the most common in female patients;young and middle-aged patients were most common with dampness-heat constitution,and elderly patients were most common with yang-deficiency constitution.There was no correlation between physical constitution type and ulcer location,number,size,congestion and edema of surrounding mucosa,bleeding and ball deformation(P>0.05),but there was a statistical difference between the ulcer surface coating and mucosal erosion(P<0.05).Those with thick yellow coating on the surface of the ulcer were more common with dampness-heat constitution,and those with thin white coating were more common with yang-deficiency constitution;those with mucosal erosions were most common with dampness-heat constitution.5.There was a correlation between TCM syndrome types and constitution types of DU.Stomach yin deficiency syndrome was related to yin-deficiency constitution,spleen-stomach dampness-heat syndrome was related to dampnessheat constitution,stomach stasis syndrome was related to blood stasis constitution,liver-stomach disharmony syndrome was related to qi-depression constitution and qi-deficiency constitution,liver-stomach stagnation-heat syndrome was related to gentleness constitution,allergic constitution and phlegm-dampness constitution,spleen-stomach weakness(cold)syndrome was related to yang-deficiency constitution and qi-deficiency constitution;Patients with dampness-heat constitution were easy to develop into spleen-stomach dampness-heat syndrome,and patients with qi-deficiency constitution and yang-deficiency constitution were easy to develop into spleen-stomach weakness(cold)syndrome.Yang-deficiency constitution was not easy to develop into spleen-stomach dampness-heat syndrome,liver-stomach stagnation-heat syndrome,and liver-stomach disharmony syndrome.The dampness-heat constitution was not easy to develop into the syndrome of spleen-stomach weakness and the liver-stomach disharmony.Qi-deficiency constitution syndrome was not easy to develop into liver-stomach disharmony syndrome,while stomach stasis syndrome and stomach yin deficiency syndrome were not related to the five main constitutions.Conclusion:1.DU mainly occurs in middle-aged and elderly people,and there are significantly more males than females.There are correlations between DU TCM syndrome types and physical constitution types with gender and age.The most common syndromes are spleen-stomach weakness(cold)syndrome and spleen-stomach dampness-heat syndrome.The most common constitutions are yang-deficiency constitution and dampness-heat constitution.2.There is a certain correlation between endoscopic performance of DU and TCM syndrome types and physical constitution types,patients with thick yellow coating on the surface of the ulcer have heavier dampness-heat manifestations,and those with thin white coating on the surface of the ulcer show a weakness performance.The relationship between them can be used to guide clinical practice.3.Weakness of the spleen and stomach is the basis of the of DU,and dampness heat is an important pathological factor.Therefore,clinical treatment can start from these two aspects,clearing heat and dampness to solve the target of the disease,and never forgetting to protect the spleen and stomach to prevent and cure it. |
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