Jaundice Animal Model And The Traditional Chinese Medicine In Chinese Medicine Yin Jaundice Jaundice Impact Model Of Experimental Research

Objects: To establish an animal model of TCM jaundice of Yin-Huang and discuss the effect of Chinese herbal which were applied to the animal model of TCM jaundice of Yin-Huang.Materials and Methods: We got the animal model of TCM jaundice of Yin-Huang in rats, which lived in the damp and cold environment and ig. With Rhizoma , with the injury of liver induced by oral APIT. We observe the general biological state, liver function, humoral immunity, .and the changes after treating with Chinese herbal decoction ( " Yinchenzhufu " decoction) in rat. The model was evaluated with etiologic factor, sumptom, sign, experimental data, and the disproof of treating with herbal decoction. Results: The model of TCM jaundice of Yin-Huang in rat fit the character of jaundice, which didn' t change key point marke of jaundice model, didn' t effect chief behavior of APIT jaundice model. The rats of the model all have the symptoms of cold -dampness syndrome and have the significant changes in experimental data of cold -dampness syndrome. The experimental data of jaundice and cold-dampnesssyndrome are both improved significantly treating with herbal decoction.Conclusion: The animal model of TCM jaundice of Yin-Huang in rats, which lived in the cold and damp environment and ig. with Rhizoma , with the injury of liver induced by oral APIT is in accord with the TCM theory in etiology and pathology and similar with the clinical symptom in human. It is suitable and potentially useful in the study of TCM treatment of jaundice.