Clinical Study On The Treatment Of Facial Hormone-dependent Dermatitis (fire Poison Flaming Syndrome) With Ancient Prescription Babao Wudan Medicinal Ink

Objective:To observe the clinical efficacy and safety of the treatment of syndrome of intense and exuberant fire toxin of the facial corticosteroid addictive dermatitis with the internal treatment of gufang babaowudan with inking for the treatment of facial corticosteroid addictive dermatitis.Methods:The 70 patients with facial corticosteroid addictive dermatitis who met the test requirements were numbered 1-70 in order at the time of treatment.They were divided into the control group and the test group according to the proportion of 1:1,using the computer random number table method.In the test group,the drug was taken orally,twice a day,0.5g/time.4 weeks was one course of treatment,and patients in both groups were treated continuously for 2 courses.The subjective symptoms,objective symptoms and TCM syndrome scores of the two groups were observed and recorded,and the VISIA skin analyzer was used to detect and evaluate the red area and texture to evaluate the clinical efficacy.At the same time,the possible adverse reactions were observed and recorded in this clinical study,and the safety of the two groups of patients was evaluated before and after treatment.After the completion of the study,the experimental data of the subjects participating in the clinical study were collated,and SPSS23.0 software system was used to establish a relevant database and conduct statistical analysis of the data,so as to evaluate the clinical efficacy and safety of the treatment of facial hormone-dependent dermatitis with the use of Babaowudanyaomo.Results:The 70 patients strictly included completed all the courses of treatment according to the clinical study plan,and no cases were dropped,discontinued or terminated.Baseline data of patients in the control group and the experimental group,including gender,age and disease course,showed no significant difference(all P values were>0.05)by statistical test,suggesting comparability.Improvement of clinical symptoms:the comparison of subjective symptoms,objective symptoms,total symptom scores,TCM symptoms,VISIA(red area,texture)between the two groups before treatment showed no statistically significant difference(all P values were>0.05).The subjective symptoms,objective symptoms,total symptom scores and clinical effective rate of the control group and the treatment group at 4 weeks and 8 weeks of treatment were all improved compared with those before treatment,and the differences were statistically significant(all P values<0.05).There was no statistically significant difference between the control group and the experimental group in terms of subjective symptoms,objective symptoms,total symptom scores and clinical effectiveness(all P values were>0.05).The comparison of subjective symptoms,objective symptoms and total symptom scores between the control group and the experimental group after 8 weeks of treatment showed statistically significant differences(all P values were<0.05).The total effective rate was 94.29%in the experimental group and 77.14%in the control group for 8 weeks,with statistically significant differences(P<0.05).Compared with the results of VISIA skin test analyzer,the experimental group was superior to the control group in terms of red area,absolute value of texture image count and TCM symptoms after treatment,with significant differences(P values of>0.05).Safety:no drug-related or possibly drug-related adverse reactions were found in the study,and there were no abnormal changes in blood routine and liver and kidney functions of the patients before and after the study.Both of the two treatment methods were safe.Conclusion:Poison control group and experimental group can obviously improve the syndrome of intense and exuberant fire toxin of the facial corticosteroid addictive dermatitiss of subjective symptoms,objective symptoms,TCM symptoms and VISIA(red zone,texture)score,but overall is better than that of control group,experimental group showed that sweet five bravery and medicine in the treatment of flaming fire poison ink card is better than that of compound glycyrrhizin glucoside in hormone-dependent facial dermatitis,for the clinical treatment of hormone-dependent facial dermatitis provides a new method of more safe and effective treatment.