Study On The Distribution Characteristics And Clinical Correlation Of TCM Constitution In Diabetic Foot

Objective:The difference of TCM Constitution distribution between the two groups was compared and analyzed.The difference of TCM Constitution in age,gender and shape distribution between the two groups was compared and analyzed,and the difference of laboratory indexes between different constitution of diabetic foot group was analyzed,by collecting the TCM Constitution,general condition,disease information and laboratory indexes of diabetic foot group in two groups of diabetic foot group and non-diabetic foot group.Objective to investigate the distribution of TCM Constitution of diabetic foot and the correlation between TCM Constitution and clinical indicators of diabetic foot,so as to provide a theoretical basis for the prevention of diabetic foot.Method:A total of 201 questionnaires were included in this study.They were divided into non diabetic foot group(group NDF)and diabetic foot group(group DF),according to whether the diabetic foot was combined.Among them,there were 94 cases in NDF group and 107 cases in DF group.(1)General information collection:gender,age,course of disease,smoking history,drinking history,hypoglycemic regimen and other general information were collected.height and weight were measured,and body mass index(BMI)was calculated.(2)collection of disease information:collect past history of included casea,including hypertension history,hyperlipidemia history,hyperuricemia history,record whether diabetic retinopathy(DR),diabetic nephropathy(DN)and diabetic peripheral neuropathy(DPN),record Wagner classification,gangrene typing and TCM syndrome type of diabetic foot group;(3)collection of laboratory indicators:record total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL-C),high-density lipoprotein(HDL-C),blood uric acid(UA),urea nitrogen(BUN),serum creatinine(SCr),fasting blood glucose(FBG),albumin(ALB),hemoglobin(HGB)and other laboratory indicators in diabetic foot group.The above data were analyzed by SPSS 25.0.Result:1.Comparison of TCM Constitution distribution between NDF group and DF group:(1)In the overall distribution of TCM Constitution,the main constitution types of NDF group were qi deficiency(26.6%),yin deficiency(21.3%)and damp heat(16%),while those of DF group were Yin deficiency(22.4%),phlegm dampness(19.6%)and blood stasis(18.7%).The proportion of blood stasis in DF group was higher than that in NDF group(P=0.009),and the proportion of damp heat in NDF group was higher than that in DF group(P=0.008);(2)In terms of gender distribution,there was no significant difference in the distribution of female constitution between the two groups.The proportion of male damp heat constitution in NDF group was higher than that in DF group(P=0.001),and the proportion of male blood stasis constitution in DF group was higher than that in NDF group(P=0.014);(3)In terms of age distribution,the proportion of qi deficiency in NDF group was higher than that in DF group(P=0.029);(4)In the body distribution,the proportion of damp heat constitution in NDF group was higher than that in DF group(P=0.011),and the proportion of qi deficiency constitution:in obesity group(BMI>28kg/m2)was higher than that in DF group(P=0.023).2.The correlation between body constitution and laboratory indexes in diabetic foot group:Compared with the patients with phlegm dampness,the patients with qi deficiency,yang deficiency and blood stasis had lower TC(P<0.05);Compared with patients with phlegm dampness,LDL-C in patients with qi deficiency and blood stasis was lower(P<0.05);Compared with the patients with yin deficiency,the FBG of patients with phlegm dampness and yang deficiency decreased(P<0.05).There was no significant difference in the distribution of UA,bun,SCR,ALB,HGB,TG and HDL-C in DF group(P>0.05).3.The correlation between constitution and various factors in diabetic foot group:In DF group,yin deficiency was positively correlated with fasting blood glucose(P=0.001,OR=1.223);In DF group,there was a positive correlation between phlegm dampness and total cholesterol(P=0.001,OR=2.389),and a negative correlation between phlegm dampness and fasting blood glucose(P=0.015,OR=0.787).Conclusion:1.NDF group and DF group had the constitution of qi deficiency and yin deficiency in the top four physique distribution,suggesting that there was a certain correlation between the susceptible constitution of the two groups.But the difference in the overall distribution between the two groups was statistically significant.The proportion of blood stasis in the DF group was higher than that in the NDF group,and the ratio of damp heat to mass in the NDF group was higher than that in the diabetic foot group,suggesting that blood stasis may be the susceptible constitution of DF.2.There are differences in the distribution of the same constitution of the same sex,age and body between NDF group and DF group.3.In DF group,the TC and LDL-C of phlegm dampness constitution were higher,and the FBG of yin deficiency constitution was higher.