Intervention Effect And Mechanism Of Five-element Angle Music On Psoriasis With Qi Depression

ObjectiveTo observe the intervention effect of wuxingjiaodiao music on qiyuzhi psoriasis and explore its mechanism.MethodsFrom December 2019 to February 2021,40 patients with qi stagnation psoriasis were recruited in Beijing Hospital of traditional Chinese Medicine Affiliated to Capital Medical University.They were randomly divided into two groups,namely,the five element tune music group(experimental group)and the conventional treatment group(control group),with 20 patients in each group.On the basis of conventional treatment,the patients in the experimental group were intervened with five elements music,once a day for 45 minutes,for a total of 4 weeks.Self rating Anxiety Scale(SAS),heart rate variability(HRV),serum cortisol(SC),PASI score and quality of life scale(QOL)score were used as the observation indexes.The scores of 1 day before intervention and 28 days after intervention were recorded,and the therapeutic effects of different groups were compared.ResultsThe basic information of the two groups,including age,gender and course of disease,had no significant difference and was comparable(P>0.05).1.The SAS scores of the two groups before and after the intervention were compared.The experimental group decreased significantly with significant difference(P<0.01),while the control group decreased slightly with no significant difference(P>0.05).There was no significant difference in SAS score among patients with different anxiety levels in the experimental group(P>0.05).2.Compared the DLQI scores of the two groups before and after the intervention,the experimental group decreased significantly(P<0.01),and the control group increased significantly(P<0.05).3.The PASI scores of the two groups before and after the intervention were compared,the experimental group was significantly lower,with significant difference(P<0.01),and the control group was significantly lower,with significant difference(P<0.05);There was no significant difference in PASI score between the two groups on the 28th day after intervention(P>0.05).There was no significant difference between the two groups before and after the intervention(P>0.05).4.The serum cortisol of the two groups before and after the intervention was compared.For the patients whose cortisol level was higher than the normal value,the experimental group was significantly lower,with significant difference(P<0.01),while the control group was higher,with no significant difference(P>0.05);For patients with normal cortisol level,the experimental group was higher than before,the difference was not significant(P>0.05),the control group was significantly higher,the difference was significant(P<0.05).5.Compared the heart rate variability of the two groups before and after the intervention,the LF value of the experimental group increased significantly,with significant difference(P<0.01),while the LF value of the control group decreased,with no significant difference(P>0.05);The HF value of the experimental group increased significantly(P<0.01),and that of the control group increased significantly(P<0.05);On the 28th day after the intervention,the HF value of the experimental group was significantly higher than that of the control group(P<0.01);The LF value of the experimental group before and after intervention was significantly higher than that of HF value;The LF/HF value of the experimental group increased significantly(P<0.05),while the LF/HF value of the control group decreased slightly(P>0.05);The RMSSD value of the experimental group increased significantly(P<0.01),and the RMSSD value of the control group decreased significantly(P<0.05).ConclusionThe results showed that:1.Five elements music can effectively reduce PASI score and improve the quality of life of patients with qiyuzhi psoriasis.2.The music can improve the heart rate variability and autonomic nervous function of psoriasis patients with qiyuzhi.3.The music of five elements can reduce the content of serum cortisol in patients with qiyuzhi psoriasis,and then reduce their anxiety.