Risk Factors Of Abdominal Allergic Purpura And Gastrointestinal Bleeding In Children

Objective:To study the risk factors affecting the occurrence of abdominal allergic purpura and gastrointestinal bleeding in children.To identify independent risk factors for early diagnosis and treatment,prevention of complications and improvement of prognosis.Methods:Children with henoch schonlein Purpura who were hospitalized in the Department of Pediatrics of The First Hospital of Lanzhou University from December 2016 to September 2021 were selected.All the children were recorded with general condition and related laboratory examination results.Abdominal purpura was divided into abdominal purpura gastrointestinal bleeding group and no gastrointestinal bleeding group according to the presence or absence of gastrointestinal bleeding.The risk factors of abdominal purpura and gastrointestinal bleeding were analyzed.Statistical analysis was performed.The independent risk factors were identified by univariate and multivariate analysis.ROC curve was drawn to evaluate the AUC value,sensitivity and specificity of the prediction model.Results:1.Analysis of risk factors for the occurrence of abdominal purpura showed statistically significant differences in gender,length of stay,CRP,WBC,L#,M#,N#,E#,NLR,PLT,PLR,PCT,AST,ALT,ALB,NA,ASO,AT,APTT,D-D,FDP,etc.,P<0.05.Female,increased NLR ratio and increased D-D value were independent risk factors.The risk of abdominal purpura was increased when NLR>1.88 and D-D>1.51ug/m L.2.Analysis of risk factors for gastrointestinal bleeding of abdominal type purpura:There were statistically significant differences in length of hospital stay,whether there was an inducement,abdominal pain as the first symptom,melena,hematemesis,CRP,WBC,L#,N#,E#,NLR,HB,PLT,PLR,ESR,PCT,AST,ALT,ALB,GLB,NA,IGG,IGA,D-D,FDP,etc.,P<0.05.Among them,abdominal pain as the first symptom,melena,increased WBC,and increased NLR ratio are independent risk factors for abdominal purpura gastrointestinal bleeding.When WBC>11.8×10~9/L and NLR>2.11,the risk of gastrointestinal bleeding of abdominal purpura was increased.Conclusion:1.Female,NLR>1.88,D-D>1.51ug/m L were risk factors for abdominal purpura.2.Abdominal pain as the initial symptom,WBC>11.8×10~9/L and NLR>2.11 were independent risk factors for gastrointestinal bleeding in abdominal purpura.