Analysis Of Prognostic Risk Factors For Neonatal Seizures In A Third-class Hospital In Enshi

Objective To study the common risk factors affecting the prognosis of neonatal seizures and to provide a basis for early diagnosis,treatment and intervention of the disease.Methods: Clinical data were collected from 124 children with confirmed neonatal convulsions who were hospitalized in the neonatal unit of Enshi Central Hospital from 01/01/2016 to 12/31/2020 with complete data and at least 1 year of follow-up,and the neonatal were divided into 3 groups according to the degree of v EEG abnormality,including 48 cases in the mild abnormality group,46 cases in the moderate abnormality group,and 30 cases in the severe abnormality group,and the general data,v EEG and other clinical data of the children in the three groups were compared,and the data were processed by applying SPSS analysis.Results 1.The more severe the degree of v EEG abnormality,the higher the rate of recurrent convulsions and developmental delay in children（P < 0.05）.2.There were no statistically significant differences in gender,race,place of residence,birth weight,gestational age,number of births,mode of conception,Abnormal umbilical cord,abnormal placenta,history of infection during pregnancy,age of first onset and premature rupture of membranes among the three groups of children（P >0.05）.3.Birth asphyxia,pregnancy complications,1-minute Apgar score,5-minute Apgar score,abnormal amniotic fluid,seizure form,number of seizures,duration of each seizure,etiology,and type of EEG abnormality were the main factors affecting the prognosis of convulsed neonates（P < 0.05）.Further logistics regression analysis yielded that abnormal amniotic fluid,5-minute Apgar score,type of v EEG abnormality,seizure form,number and duration of each seizure were associated risk factors for poor prognosis.Conclusions: 1.v EEG severity is good for prognostic assessment of children and is expected to become the excellent standard for early prognostic assessment of children with convulsions.2.Amniotic fluid abnormality,5-minute Apgar score,abnormal type of v EEG,seizure form,number and duration of each seizure are associated risk factors for poor prognosis,and asphyxia is the main cause of convulsions in children in this region.At the same time,Children with convulsions caused by asphyxia generally have a better prognosis and should be treated accordingly to improve their prognosis.